Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Systemic Granulomatosis in Argyrosomus regius

ABSTRACT: Investigation of Systemic Granulomatosis in cultured meagre, Argyrosomus regius using clinical metagenomics

PROVIDER: PRJEB43864 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR5529910_1.fastq.gz	Fastqsanger.gz
	ERR5529910_2.fastq.gz	Fastqsanger.gz
	ERR5529920_1.fastq.gz	Fastqsanger.gz
	ERR5529920_2.fastq.gz	Fastqsanger.gz
	ERR5529930_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 58

Similar Datasets

Argyrosomus regius

Project description:Argyrosomus regius overview

| PRJNA1188681 | ENA

Argyrosomus regius

Project description:Argyrosomus regius Transcriptome or Gene expression

| PRJNA399060 | ENA

Genome Assembly for the Meagre, Argyrosomus regius

Project description:Argyrosomus regius Genome

| PRJEB56176 | ENA

Comprehensive transcriptome profiling and functional analysis of the meagre (Argyrosomus regius) immune system

Project description:Meagre (Argyrosomus regius) belongs to the family Sciaenidae and is a promising candidate for Mediterranean aquaculture diversifcation. As a relatively recent species in aquaculture, the physiological consequences of the immune system activation in meagre are understudied. Spleen, as a primary lymphoid organ has an essential role in meagre immune and inﬂammatory responses. In this study, we have evaluated the in vivo effects of lipopolysaccharide (LPS) on the spleen transcriptome of meagre by RNA-seq analysis at 4 and 24 h after injection. The assembled transcripts were assigned to immunological processes. At 24 h, the number and type of differential immune-related genes regulated by LPS was higher than at 4 h. However, at 4 h the upregulation of immune-related genes was greater. Several genes related to the innate immune response were upregulated including tolllike receptor 5, and multiple interferons and interferon-related proteins. In the present work, it was shown that several chemokines and chemokine ligands (e.g. cxcl10, ccl21) as well as cytokines (e.g. il1b, il12, il27) were overexpressed as a result of LPS injection, supporting their role as mediators of the innate and adaptive immune response. KEGG analysis found that LPS-stimulated immune responses mainly involve cytokine and protein-protein interactions involved in pathogen response. Specifcally, genes involved in the MHCI and MHCII pathways were induced as early as 4 h post LPS injection. These results will help to understand the pathogenesis and host defense system in meagre.

2024-11-20 | GSE247868 | GEO

Male germ cell proliferation and apoptosis in sexually immature meagre Argyrosomus regius (Asso, 1801) treated with recombinant follicle stimulating hormone

Project description:Argyrosomus regius transcriptome data

| PRJEB57583 | ENA

Comprehensive transcriptome profiling and functional analysis of the meagre (Argyrosomus regius) immune system

Project description:Comprehensive transcriptome profiling and functional analysis of the meagre (Argyrosomus regius) immune system

| PRJNA1040844 | ENA

Argyrosomus japonicus

Project description:Argyrosomus japonicus

| PRJNA611881 | ENA

Expression data from human Wegener’s granulomatosis patients and normal controls in PBMCs and in PMNs

Project description:Wegener’s granulomatosis (WG) is a systemic inflammatory disease that can lead to substantial morbidity. This study seeks to further understanding of the biology underlying WG, and to discover markers of disease activity useful in prognosis and treatment guidance.

2010-03-05 | GSE18885 | GEO

Cinnyris regius

Project description:Cinnyris regius

| PRJNA921026 | ENA

Lamprotornis regius

Project description:Lamprotornis regius

| PRJNA960039 | ENA