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ABSTRACT: Reads from ERS2445851 supporting inference of IGHV4-39*01_C66G allele

PROVIDER: PRJEB44653 | ENA |

REPOSITORIES: ENA

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Source:

			Action	DRS
	ERR5948282_1.fastq.gz	Fastqsanger.gz
	ERR5948282_2.fastq.gz	Fastqsanger.gz

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RNA-seq analysis of Chronic Lymphocytic Leukemia patients belonging to stereotyped subsets #6 and #8

Project description:Chronic lymphocytic leukemia (CLL) stereotyped subsets #6 and #8 include cases expressing unmutated B cell receptor immunoglobulin (BcR IG) (U-CLL). Yet, subset #6 (IGHV1-69/IGKV3-20) is less aggressive compared to subset #8 (IGHV4-39/IGKV1(D)-39) which has the highest risk for Richter’s transformation among all CLL. The underlying reasons for this divergent clinical behavior are not fully elucidated. To gain insight into this issue, here we focused on their gene expression profiling and performed RNA-seq.

2019-04-04 | E-MTAB-6962 | biostudies-arrayexpress

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