Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Dutch equine faecal microbiota

ABSTRACT: The equine faecal microbiota of healthy horses and ponies in the Netherlands: impact of host and environmental factors

PROVIDER: PRJEB44895 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR5909160_1.fastq.gz	Fastqsanger.gz
	ERR5909160_2.fastq.gz	Fastqsanger.gz
	ERR5909170_1.fastq.gz	Fastqsanger.gz
	ERR5909170_2.fastq.gz	Fastqsanger.gz
	ERR5909180_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 216

Similar Datasets

Gene expression profiling in equine polysaccharide storage myopathy

2009-04-08 | GSE15572 | GEO

Gene expression profiling in equine polysaccharide storage myopathy

Project description:Standardized muscular biopsies of the dorsal compartment of the gluteus medius muscle were performed in 7 horses suffering from equine polysaccharide storage myopathy (PSSM) and 6 sound Norman Cob horses . Gene expression analysis was performed using an equine oligonucleotide microarray which included 384 equine gene probes of the nuclear genome and all the mitochondrial genes. All the samples of PSSM muscles were hybridized against the reference control muscles. This reference was made by pooling together all the mRNA extracted after in vitro transcription from the 6 control muscles of the sound horses. Briefly, the hybridization protocol was adapted from Le Brigand et al. (2006). An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes. Nucleic Acids Res. 2006 Jul 19;34(12).

2009-04-08 | E-GEOD-15572 | biostudies-arrayexpress

Cellular and viral transcription profiles in Equine Papillomavirus Type 2 positive squamous cell carcinomas

Project description:Equine Papillomavirus Type 2 (EcPV2) appears to be a causal factor for the development of genital especially penile squamous cell carcinomas (SCC) and as such have an important clinical impact on horses. However, the pathomechanisms associated with this cancer transformation are not known, yet. To analyze the host’s and viral transcriptome in EcPV2 affected horses, tissue samples were collected from horses with EcPV2-positive genital lesions as well as from healthy EcPV2-negative horses. Expression levels of host and viral genes were evaluated by RNA-Seq.

2019-12-03 | GSE123533 | GEO

Mucosal immune response against equine herpesvirus type 1

Project description:To investigate pre-existing mucosal immunity in equine herpesvirus type 1 (EHV-1) immune and non-immune horses during experimental viral challenge. RNAseq was performed on nasal mucosal swab samples from immune and non-immune horses from pre (d-2), early (d1pi and d3pi), mid (d8pi and d10pi), and late (d18pi) infection.

2024-05-08 | GSE232941 | GEO

Pathways involved in pony body size development

Project description:The mechanism of body growth in mammals is poorly understood. Here, we report the regulatory networks involved in body growth through analyzing transcriptomes of pituitary and epiphyseal tissues of Debao ponies and Mongolian horses at juvenile and adult stages. We found that GHR was expressed little in long bones though GH was highly expressed in Debao ponies compared with Mongolian horses. Moreover, m-RAS and ATF3, involved in the GHR pathway, were found to be significantly downregulated in juvenile ponies, which slowed the proliferation of bone osteocytes. However, WNT2 and PLCβ2 were obviously upregulated in juvenile Debao ponies, which led to premature mineralization of bone extracellular matrix. Furthermore, we found that the WNT/Ca2+ pathway may be responsible for the regulation of body growth. We then demonstrated that GHR was lacking in long bones of Debao ponies using RT-qPCR and Western blot. Treatment with WNT antagonist 1 decreased expression of the WNT pathway (P≤0.05) in vitro. The transduction of ATDC5 cells with GHR-RNAi lentivirus decreased expression of the GHR pathway (P≤0.05). Additionally, detection of plasma hormone concentrations showed that the ponies had higher levels of IGF-1 as juveniles and GH in adulthood than Mongolian horses, indicating that the hormone regulation in Debao ponies differs from that in Mongolian horses. Our work provides an insight into the genetic regulation for dwarf growth in mammals and a reference for therapeutic strategy for dwarfism

2021-01-27 | GSE146145 | GEO

Reduced representation bisulfite sequencing of equine sarcoid and tumor distant skin samples

Project description:The aim of the project was to identify sites undergoing changes in methylation level in cancer cells of equine sarcoid. The comparative analysis of DNA methylation patterns of the genome fraction rich in CpG dinucleotides was investigated using Reduced Representation Bisulfite Sequencing (RRBS) technique. In this study, for the first time we report the genome-wide DNA methylation profile of skin tumour in horses and describe differentially methylated genomic regions with respect to healthy skin.

2017-05-31 | GSE89859 | GEO

Grass sickness equine faecal bacteria sequencing data.

Project description:Explore the effect of grass sickness on the equine faecal microbiome.

| PRJEB11642 | ENA

A composite map of copy number variable (CNV) regions in the horse genome and the discovery of CNVs involved in equine XY disorders of sexual development

Project description:38 horses from 16 diverse breeds and Przewalski's Horse were used to generate a composite CNV map of equine genome. This map was used to detect novel copy number variation in six horses affected with disorder of sexual development (DSD).

2014-11-07 | GSE55266 | GEO

equine CD4+ T cells show changed membrane protein expression in autoimmune uveitis

Project description:Through this comparative proteomic study of equine CD4+ cells 376 membrane proteins could be identified. Several proteins showed changed abundance in horses affected by a spontaneous autoimmune disease (equine recurrent uveitis, ERU). Findings provide novel knowledge about changes in the CD4+ immune cell membrane proteome in a spontaneously and naturally occurring autoimmune disease in horses. The data is highly relevant for veterinary medicine and has proven translational quality for autoimmune uveitis in man.

2017-01-09 | PXD005384 | Pride

Class I integrons, plasmids, and resistance genes in faecal bacteria from wild, domesticated, and veterinary equine cohorts

Project description:Integrons in equine faecal bacteria

| PRJEB55090 | ENA