Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Sperm DNA methylation of bulls of the Montbeliarde breed

PROVIDER: PRJEB46371 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	ERR6511490_1.fastq.gz	Fastqsanger.gz
	ERR6511490_2.fastq.gz	Fastqsanger.gz
	ERR6511500_1.fastq.gz	Fastqsanger.gz
	ERR6511500_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 239

Similar Datasets

Divergences of sperm DNA methylomes between monozygotic twin seed bulls reveal fertility-related genes (WGBS)

Project description:The sperm DNA methylomes of the MZ twin bulls were investigated by WGBS at single-base resolution. We detected DMRs between the twin bulls with divergent sperm qualities. We also conducted transcriptome sequencing for the MZ twin bulls in three replicates. We investigated the relationship between methylation and gene expression.

2020-01-01 | GSE131850 | GEO

Divergences of sperm DNA methylomes between monozygotic twin seed bulls reveal fertility-related genes (RNA-Seq)

Project description:Semen quality is extremely important for fertility, and it is easily influenced by environmental factors and can induce subfertility of the next generations. The sperm DNA methylomes of the MZ twin bulls were investigated by WGBS at single-base resolution. We detected DMRs between the twin bulls with divergent sperm qualities. We also conducted transcriptome sequencing for the MZ twin bulls in three replicates. We investigated the relationship between methylation and gene expression.

2020-01-01 | GSE131849 | GEO

Comparative analyses of sperm DNA methylomes among three commercial pig breeds reveal vital hypomethylated regions associated with spermatogenesis and embryonic development

Project description:This study is the first to report a genome-wide comparative DNA methylation map of adult pig sperm in three commercial pig breeds using WGBS technology. Our results showed that DNA methylation was more conserved in the three commercial pig breeds. Moreover, our results indicated that breed-specific HMRs are related to phenotypic changes and economically complex traits for each breed. The conserved HMRs between pig sperm and testis close to or located in the promoter regions of important genes are mainly involved in DNA repair and spermatogenesis.

2023-07-01 | GSE180099 | GEO

Cold exposure impacts DNA methylation patterns in cattle sperm

Project description:Epigenetic markers, such as DNA methylation, in sperm plays crucial roles in spermatogenesis and fertilization, and a portion of methylation escape the early embryonic genome-wide DNA demethylation and affect later growth and development of offspring. DNA methylation is influenced by various exogenous factors such as nutrition, temperature, toxicants, and stress. The effects of this cold exposure on the methylation dynamics of bovine sperm remain unexamined. Methylation profiles of sperm, collected from bulls during summer and winter seasons were analyzed by Whole Genome Bisulfite Sequencing (WGBS). Cold exposure during winter does not have a significant effect on the global methylation level, it altered the methylation levels at certain genomic loci and genes that may impact the maintenance of methylation status of imprinted genes and other loci, which may impact the development and growth of offspring.

2024-01-31 | GSE222863 | GEO

Genome wide differential H3K4me2 and H3K27me3 profile of spermatozoa from high and sub-fertility buffalo bulls

2014-12-24 | GSE49316 | GEO

DNA methylation analysis of bull semen according to peripubertal age (10 months vs. 16 months)

Project description:The DNA methylation pattern in spermatozoa of bulls at different age was investigated. Spermatozoa collected from 4 different bulls at 10, 12 and 16 month each. Genome-wide DNA methylation analysis was performed by micro array using EDMA platform. three condition experiment, 4 bulls, all collected at 10, 12 and 16 month

2016-02-24 | E-GEOD-78231 | biostudies-arrayexpress

DNA methylation analysis of bull semen according to peripubertal age (12 months vs. 16 months)

2016-02-24 | E-GEOD-78232 | biostudies-arrayexpress

Bos taurus

Project description:Genome-wide analysis of sperm DNA methylation from monozygotic twin bulls

| PRJNA299310 | ENA

Whole genome methylation sequencing for daughter fertility DNA mehylation biomarker

Project description:high daughter fertility and low daughter fertility bulls were screened from the private bull database and then identify the sperm-derived DMR and DMC that associated with daughter fertility via whole genome methylation sequencing

2023-08-23 | GSE211926 | GEO

Genome wide profiling of buffalo (Bubalus bubalis) sperm DNA methylation in relation to bull fertility

Project description:Sperm carries information to the presumptive embryo upon fertilization in terms of epigenetic codes and transcripts along with the haploid genome. The epigenetic code includes DNA methylation and histone modifications. During spermatogenesis, the DNA of sperm undergoes overall methylation changes and this could have some role to play in fertilizing ability of the sperm. Many of the studies have shown that the altered methylation can cause sub fertility. In the present study we report the development of first comprehensive 4X180K buffalo (Bubalus bubalis) CpG island/promoter microarray for studying the global DNA methylation profile of buffalo sperm. The array has been developed by employing microarray based comparative genomic hybridization (aCGH) technique with bovine and buffalo DNA using bovine genome sequence as reference. The array represents 157084 features assembled from CDS, Promotor and CpG regions covering 2,967 unique genes. We also report the comparison of genome wide methylation differences in buffalo sperm from high fertile and sub fertile bulls which indicated profound discrepancies in their methylation status. A total of 96 individual genes along with another 55 genes covered under CpG islands were found differentially methylated and and were associated with different cellular functions and biological processes affecting germ cell development, spermatogenesis, capacitation and embryonic development.

2014-12-24 | GSE46460 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data