Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Ribo-seq of human colorectal cancer cell line HCT116/L-OHP against HCT116

ABSTRACT: Ribo-seq of human colorectal cancer cell line HCT116/L-OHP against HCT116

PROVIDER: PRJEB46746 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR6391420_1.fastq.gz	Fastqsanger.gz
	ERR6391420_2.fastq.gz	Fastqsanger.gz
	ERR6391421_1.fastq.gz	Fastqsanger.gz
	ERR6391421_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

Ribo-seq of human colorectal cancer cell line HCT116/L-OHP against HCT116

Project description:Oxaliplatin (L-OHP) serves as a standard chemotherapy for colorectal cancer, while the drug resistance is still a considerable challenge. Dysregulation of lncRNA is involved in cancer and recent translatomics has found some alleged lncRNA actually contained small open reading frames and could encode short peptides. This ribosome footprint profiling (Ribo-seq) was a paired-end sequencing and aimed to investigate whether lncRNA could regulate oxaliplatin resistance in colorectal cancer by encoding short peptides.

2021-11-12 | E-MTAB-10805 | biostudies-arrayexpress

RNA-seq of human colorectal cancer cell line HCT116/L-OHP against HCT116

Project description:RNA-seq of human colorectal cancer cell line HCT116/L-OHP against HCT116

| PRJEB46747 | ENA

ZKSCAN3 knockout HCT116 colorectal cancer cell line

Project description:ZKSCAN3 knockout HCT116 colorectal cancer cell line

| PRJNA722415 | ENA

Genome-wide profiling of HCT116 colorectal carcinoma cell line with nu7441 treatment

Project description:Identification of genes and pathways that were influenced by nu7441, the PRKDC inhibitor, in HCT116 colorectal carcinoma cell line.

2018-08-03 | GSE93074 | GEO

The effect of VGLL4 on HCT116 colorectal cancer cell line

Project description:VGLL4, a tumor suppressor, is negative regulator of Hippo/YAP signaling. To explore the role of VGLL4 during colorectal cancer cell line, we explore microarray analysis of HCT116 cells after stable transfection of VGLL4 and shVGLL4 for 48 h.

2017-02-08 | GSE81665 | GEO

Methylome analysis of colorectal cancer cell line DNA (HCT116) and colorectal cancer patient derived xenografts (PDXs) using MeDIP-seq and cfMeDIP-seq

Project description:Three separate experiments were carried out using MeDIP-seq and cfMeDIP-seq for methylome analysis. For the first experiment, different starting amounts of HCT116 cell line DNA, sheared to mimic cell-free DNA, were analyzed using MeDIP-seq and cfMeDIP-seq. In the second experiment the limit of detection of cfMeDIP-seq was tested using varying dilutions of colorectal cancer cell line DNA (HCT116) with multiple myeloma cell line DNA (MM1.S). For both cell line DNA samples, the DNA was sheared to mimic cell-free DNA. In the final experiment, we tested the enrichment of human ctDNA using cfMeDIP-seq performed on plasma collected from patient-derived xenografts (PDXs) generated in mice from two colorectal cancer patients.

2018-04-01 | GSE79838 | GEO

mRNA expression of colorectal cancer cell line HCT116 transfected with lncRNA-SPRY4-IT1 overexpression or control vector

Project description:To determine the mRNA expression profile of colorectal cancer cell line HCT116 transfected with lncRNA-SPRY4-IT1 overexpression vector, we performedd gene expression microArray analysis to examine the expression of mRNAs.

2019-11-19 | GSE140616 | GEO

Identification of genes involved in RAS oncogenic activity in human colorectal cancer cell line HCT116

Project description:The study aimed to identify genes essential for the maintenance of the transformed phenotype of the colorectal cancer cell line HCT116, which is dependent on the continued expression of the activated KRAS oncogene (KRASG13D). We generated HCT116 cell lines stably expressing an inducible shRNA-expressing retroviral vector targeting KRAS (Ngo et al., Nature, 2006). In cells engineered to express the bacterial tetracycline repressor, the shRNA is expressed specifically upon doxycycline addition. With this system, we showed that inducible down-regulation of KRAS is triggering cell death in the HCT116 cells, suggesting oncogene addiction in this cell line. In this study, we compared the gene expression profile of HCT116 cells where KRAS has been downregulated for different lengths of time, aiming at identifying RAS-target genes. We also compared the gene expression profile of the parental HCT116 cell line with two derived isogenic cell lines, Hke3 and Hkh-2, where the activated KRAS gene has been deleted by homologous recombination.

2022-04-03 | GSE199871 | GEO

Transcription profiling of human colorectal cell line HCT116 DICER Exon5 knockout cells

Project description:The experiment was to study the gene expression changes in human colorectal cell HCT116 DICER Exon5 knockout cells comparing to that in parental HCT116 cellls. Experiment Overall Design: Experiment includes using of two Agilent human 44K microarrays with dye-swap replication.

2008-06-14 | E-GEOD-6427 | biostudies-arrayexpress

Gene expression changes in human colorectal cell line HCT116 DICER Exon5 knockout cells

2007-10-26 | GSE6427 | GEO