Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Twenty-two listeriosis outbreaks with salmon products being the most likely source in Germany, 2010-2021

ABSTRACT: Listeriosis outbreaks with salmon products as the most likely source in Germany

PROVIDER: PRJEB48063 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	ERR12165300.fastq.gz	Fastqsanger.gz
	ERR12165305.fastq.gz	Fastqsanger.gz
	ERR12165294.fastq.gz	Fastqsanger.gz
	ERR12165295.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 238

Similar Datasets

Invasive listeriosis outbreaks and salmon products: a genomic, epidemiological study.

Project description:Invasive listeriosis, caused by Listeria (L.) monocytogenes, is a severe foodborne infection, especially for immunocompromised individuals. The aim of our investigation was the identification and analysis of listeriosis outbreaks in Germany with smoked and graved salmon products as the most likely source of infection using whole-genome sequencing (WGS) and patient interviews. In a national surveillance programme, WGS was used for subtyping and core genome multi locus sequence typing (cgMLST) for cluster detection of L. monocytogenes isolates from listeriosis cases as well as food and environmental samples in Germany. Patient interviews were conducted to complement the molecular typing. We identified 22 independent listeriosis outbreaks occurring between 2010 and 2021 that were most likely associated with the consumption of smoked and graved salmon products. In Germany, 228 cases were identified, of 50 deaths (22%) reported 17 were confirmed to have died from listeriosis. Many of these 22 outbreaks were cross-border outbreaks with further cases in other countries. This report shows that smoked and graved salmon products contaminated with L. monocytogenes pose a serious risk for listeriosis infection in Germany. Interdisciplinary efforts including WGS and epidemiological investigations were essential to identifying the source of infection. Uncooked salmon products are high-risk foods frequently contaminated with L. monocytogenes. In order to minimize the risk of infection for consumers, food producers need to improve hygiene measures and reduce the entry of pathogens into food processing. Furthermore, susceptible individuals should be better informed of the risk of acquiring listeriosis from consuming smoked and graved salmon products.

| S-EPMC9132468 | biostudies-literature

Gene expression profile of liver from adult and neonatal Balb/c mice after listeriosis

2013-06-01 | GSE45051 | GEO

UI-607: IIa ST8 CT5004 Listeriosis outbreak in Germany

Project description:UI-607: IIa ST8 CT5004 Listeriosis outbreak in Germany

| PRJEB35042 | ENA

Multiple synchronous outbreaks of Puumala virus, Germany, 2010.

Project description:To investigate 2,017 cases of hantavirus disease in Germany, we compared 38 new patient-derived Puumala virus RNA sequences identified in 2010 with bank vole-derived small segment RNA sequences. The epidemic process was driven by outbreaks of 6 Puumala virus clades comprising strains of human and vole origin. Each clade corresponded to a different outbreak region.

| S-EPMC3437711 | biostudies-literature

Czech Republic human listeriosis

Project description:Czech Republic human listeriosis

| PRJEB37840 | ENA

Ongoing High Incidence and Case-Fatality Rates for Invasive Listeriosis, Germany, 2010-2019.

Project description:We used 10 years of surveillance data to describe listeriosis frequency in Germany. Altogether, 5,576 cases were reported, 91% not pregnancy associated; case counts increased over time. Case-fatality rate was 13% in non-pregnancy-associated cases, most in adults ≥65 years of age. Detecting, investigating, and ending outbreaks might have the greatest effect on incidence.

| S-EPMC8386774 | biostudies-literature

Genomic surveillance of human listeriosis in Germany, 2018-2021, closed genomes

Project description:Genomic surveillance of human listeriosis in Germany, 2018-2021, closed genomes

| PRJEB57450 | ENA

Molecular Tracing to Find Source of Protracted Invasive Listeriosis Outbreak, Southern Germany, 2012-2016.

Project description:We investigated 543 Listeria monocytogenes isolates from food having a temporal and spatial distribution compatible with that of the invasive listeriosis outbreak occurring 2012-2016 in southern Germany. Using forensic microbiology, we identified several products from 1 manufacturer contaminated with the outbreak genotype. Continuous molecular surveillance of food isolates could prevent such outbreaks.

| S-EPMC5621528 | biostudies-literature

Gene expression profile of liver from adult and neonatal Balb/c mice after listeriosis

Project description:Expression profiling by microarray was used with a murine listeriosis model to better understand increased susceptibility of preterm neonates to infection. We used DNA microarray to identify genes that were differentially expressed in liver of adult and neonatal Balb/c mice after listeriosis infection. A murine listeriosis model was established. The methods for culturing and counting the Listeria monocytogenes (strain CNL 85/163) had been described in previous publications. The Listeria was injected intraperitoneally using a 1-mL U-100 insulin syringe with a 30 gauge needle. Doses of Listeria monocytogenes used were based on work by our laboratory showing that similar bacterial colony counts were obtained with 4.2 x 10^5 total Listeria per adult mouse and 150 Listeria per gram for 3 to 5 day old neonatal mice. In neonatal mice, great care was taken to void deep intraperitoneal injection towards the viscera, or across the central abdominal vessels. At specified time points, liver was removed upon animal sacrifice and immediately flash frozen in liquid nitrogen and stored at -80 degrees Centigrade. Three adult mice and three neonatal mice were used at each time point.

2013-06-01 | E-GEOD-45051 | biostudies-arrayexpress

Project description:Listeriosis outbreaks in small ruminants

| PRJNA532857 | ENA