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RNA-seq analysis comparing gene expression of unc-43(gf), unc-43(-) and egl-8(-) to the corresponding control strain in daf-2(+) and daf-2(-) background

ABSTRACT: RNA-seq analysis comparing gene expression of unc-43(gf), unc-43(-) and egl-8(-) to the corresponding control strain in daf-2(+) and daf-2(-) background

PROVIDER: PRJEB48106 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR7054190_1.fastq.gz	Fastqsanger.gz
	ERR7054190_2.fastq.gz	Fastqsanger.gz
	ERR7054191_1.fastq.gz	Fastqsanger.gz
	ERR7054191_2.fastq.gz	Fastqsanger.gz
	ERR7054192_1.fastq.gz	Fastqsanger.gz

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RNA-seq analysis comparing gene expression of unc-43(gf), unc-43(-) and egl-8(-) to the corresponding control strain in daf-2(+) and daf-2(-) background

Project description:To identify genes whose expression in Caenorhabditis elegans is regulated by unc-43/CamKII or egl-8/PLCbeta during adulthood, we performed an exploratory whole transcriptome RNA-sequencing (RNA-seq) study on unc-43(gf), unc-43(-), egl-8(-) and corresponding unc-43(+)/egl-8(+) control worms. To further account for potential influences of genetic background on unc-43/egl-8 function, these experiments were conducted in long-lived insulin-receptor defective [daf-2(-)], as well as in otherwise wildtype [i.e daf-2(+)] strains.

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