Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Multi-Omics Biomarkers in IBD

ABSTRACT: An exploratory analysis of potential multi-omics biomarkers and patterns for response to vedolizumab in IBD

PROVIDER: PRJEB55125 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR10024900_1.fastq.gz	Fastqsanger.gz
	ERR10024900_2.fastq.gz	Fastqsanger.gz
	ERR10024903_1.fastq.gz	Fastqsanger.gz
	ERR10024903_2.fastq.gz	Fastqsanger.gz
	ERR10024905_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 98

Similar Datasets

Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease [RNA-Seq]

Project description:We investigated the dynamics of gene expression in blood samples of IBD patients treated with infliximab and vedolizumab and analyzed the predictive potential regarding therapy outcome.

2022-07-26 | GSE191328 | GEO

Transcriptional behavior of regulatory T cells predicts IBD patient responses to vedolizumab therapy

Project description:Vedolizumab (VDZ) is used to treat patients with IBD but the exact way it works is not known. We studied the immune system in the blood and intestine of patients treated with VDZ and found immune characteristics that correlated with response.

2022-08-23 | GSE184593 | GEO

PSC-IBD mucosal omics

Project description:PSC-IBD mucosal biology

| PRJEB32208 | ENA

Study on the Diagnostic Value of Multi-omics Combined Detection for Precancerous Lesions of CRC

Project description:Colorectal cancer (CRC) has become one of the most common malignant tumors in the world, and the key to its prevention and control is early detection and treatment. As colorectal adenoma and inflammatory bowel disease (IBD) are the inevitable precursors of most CRC, screening for colorectal adenoma and IBD is of great importance for preventing CRC. The existing detection methods have high sensitivity for CRC, while limited in colorectal adenoma and IBD. Therefore, exploring a detection method with high sensitivity for colorectal adenoma and IBD is necessary. This project intends to use methylation detection technology, lactic acid modified omics, proteomics, metagenomics, and other omics technology, through the analysis of differences in feces and histological results in healthy volunteers, patients with non-advanced adenoma, patients with advanced adenomas, patients with IBD, and patients with CRC for early screening.

| 2747576 | ecrin-mdr-crc

Dynamics and single-cell transcriptomics of circulating immune cell populations in inflammatory bowel disease upon anti-integrin treatment

Project description:To explore cellular and transcriptional changes in circulation following vedolizumab treatment in ulcerative colitis patients: investigating inflammatory gene signatures and cell migration patterns predictive of therapeutic responses in IBD

2024-09-24 | GSE261334 | GEO

Integrated multi-omics reveals putative biomarkers of bacterial-fungal co-infections

Project description:Integrated multi-omics reveals putative biomarkers of bacterial-fungal co-infections

| PRJNA818612 | ENA

Potential blood biomarkers for chronic traumatic encephalopathy: the multi-omics landscape of an observational cohort (serum exosomes miRNA microarray data)

Project description:Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to repetitive head impacts, which is susceptible in elderly people with declined mobility, athletes of full contact sports, military personnel and victims of domestic violence. It has been pathologically diagnosed in brain donors with a history of repetitive mild traumatic brain injury (rmTBI), but cannot be clinically diagnosed for a long time. By the continuous efforts by neuropathologists, neurologists and neuroscientists in recent 10 years, an expert consensus for the diagnostic framework of CTE was proposed in 2021 funded by the National Institute of Neurological Disorders and Stroke. The new consensus contributes to facilitating research in the field. However, it still needs to incorporate in-vivo biomarkers to further refine and validate the clinical diagnostic criteria. From this, a single-center, observational cohort study has been being conducted by Tianjin Medical University General Hospital since 2021. As a pilot study of this clinical trial, the present research recruited 4 pairs of gender- and age-matched rmTBI patients with healthy subjects. Their blood samples were collected for exosome isolation, and multi-omics screening to explore potential diagnostic biomarkers in blood and its exosomes.

2022-10-18 | E-MTAB-12329 | biostudies-arrayexpress

Potential blood biomarkers for chronic traumatic encephalopathy: the multi-omics landscape of an observational cohort (serum-free RNA microarray data)

2022-10-18 | E-MTAB-12330 | biostudies-arrayexpress

Potential blood biomarkers for chronic traumatic encephalopathy: the multi-omics landscape of an observational cohort (serum exosomes RNA microarray data)

2022-10-18 | E-MTAB-12331 | biostudies-arrayexpress

Integrative Multi‑omics Analysis Reveals Candidate Biomarkers for Oral Squamous Cell Carcinoma

Project description:Integrative Multi‑omics Analysis Reveals Candidate Biomarkers for Oral Squamous Cell Carcinoma

| PRJNA775998 | ENA