Project description:To understand the ontogeny and longevity of tissue-resident macrophages in nonhuman primates (NHPs), we employ a model of autologous hematopoietic stem progenitor cell (HSPC) transplantation with HSPCs genetically modified to be marked with clonal barcodes, allowing for subsequent analysis of clonal ontogeny.

2024-02-14 | GSE246350 | GEO

Ongoing Production of Tissue-Resident Macrophages from Hematopoietic Stem Cells in Healthy Adult Macaques [ATAC-seq]

2024-02-14 | GSE246348 | GEO

A Novel Population of Human Cardiac Resident Mesenchymal Stem Cells

Project description:We describe a novel population of human adult cardiac resident stem cells (CRSCs), which are positive for W8B2 antigen, originating from human adult atrial appendages. W8B2+ CRSCs exhibit a spindle-shaped morphology, are clonogenic and able to self-renew. W8B2+ CRSCs show high expression of mesenchymal but not hematopoietic nor endothelial markers. W8B2+ CRSCs expressed GATA4, HAND2, and TBX5, but not C-KIT, SCA-1, NKX2.5, PDGFR?, ISL1 or Wilm’s tumor gene-1 (WT1). W8B2+ CRSCs can differentiate into the cardiovascular lineages and secrete various cytokines. Comparative RNA sequencing was performed using W8B2+ cell from human atrial appendages (passage 2 from 3 different patients), c-Kit+ cell from human atrial appendages (passage 2 from 3 different patients) and W8B2+ cell from bone marrow (passage 3 from 2 different patients, from PromoCell, Heidelberg, Germany).

2014-10-15 | E-GEOD-62288 | biostudies-arrayexpress

Primate Comparison Study

Project description:Comparing different primates to Human; treated vs.untreated Keywords: other

2006-01-01 | GSE2569 | GEO

Thermobispora bispora strain:GAFM-TB-ZOO

Project description:Thermobispora bispora strain:GAFM-TB-ZOO Genome sequencing

| PRJNA238584 | ENA

Thermobifida fusca strain:GAFM-TF-ZOO

Project description:Thermobifida fusca strain:GAFM-TF-ZOO Genome sequencing and assembly

| PRJNA238572 | ENA