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Prevalence of MSI and Lynch syndrome in colorectal cancer in India

ABSTRACT: Prevalence of MSI and Lynch syndrome in colorectal cancer in India

PROVIDER: PRJEB58813 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	ERR10772064_1.fastq.gz	Fastqsanger.gz
	ERR10772064_2.fastq.gz	Fastqsanger.gz
	ERR10772065_1.fastq.gz	Fastqsanger.gz
	ERR10772065_2.fastq.gz	Fastqsanger.gz

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MSI analysis of Lynch syndrome urothelial cancers

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Project description:Lynch syndrome and Familial colorectal cancer type X (FCCTX) are clinically diagnosed using the same criteria, but genomic differences exist between these two groups and the genomic profiles share similarities with their sporadic counterparts, mismatch repair (MMR) deficient and proficient tumors, respectively. Array-based comparative genomic hybridization was performed on 91 tumors, comprising 23 Lynch syndrome (AH), 23 FCCTX (AA), 23 sporadic MMR deficient (AM) and 22 sporadic MMR proficient tumors, in order to identify differences between Lynch syndrome and FCCTX.

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