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RNA-seq of kidneys from mice treated for eight weeks with the glucagon receptor antibody, REGN1193, compared to mice treated with a control antibody, REGN1945.

ABSTRACT: RNA-seq of kidneys from mice treated for eight weeks with the glucagon receptor antibody, REGN1193, compared to mice treated with a control antibody, REGN1945.

PROVIDER: PRJEB59000 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR10783400_1.fastq.gz	Fastqsanger.gz
	ERR10783400_2.fastq.gz	Fastqsanger.gz
	ERR10783401_1.fastq.gz	Fastqsanger.gz
	ERR10783401_2.fastq.gz	Fastqsanger.gz
	ERR10783402_1.fastq.gz	Fastqsanger.gz

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RNA-seq of kidneys from mice treated for eight weeks with the glucagon receptor antibody, REGN1193, compared to mice treated with a control antibody, REGN1945.

Project description:Chronic glucagon receptor inhibition induced by a glucagon receptor antibody causes decrease in mesangial cell area and increases kidney weight. To dissect the molecular mechanism underlying these effects, RNA sequencing of kidney biopsies from female mice treated for eight weeks with the glucagon receptor antibody, REGN1193, or a control antibody, REGN1945, were performed.

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RNA-seq of livers from mice treated for eight weeks with the glucagon receptor antibody, REGN1193, compared to mice treated with a control antibody, REGN1945, (control group)

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