Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mouse-adapted SARS-CoV-2 infected Lungs from wild type or genetically obese mice

ABSTRACT: Mouse-adapted SARS-CoV-2 infected Lungs from wild type or genetically obese mice

PROVIDER: PRJEB59973 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR10898439_1.fastq.gz	Fastqsanger.gz
	ERR10898439_2.fastq.gz	Fastqsanger.gz
	ERR10898440_1.fastq.gz	Fastqsanger.gz
	ERR10898440_2.fastq.gz	Fastqsanger.gz
	ERR10898441_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 18

Similar Datasets

Mouse-adapted SARS-CoV-2 infected lungs from lean or obese ob/ob mice

Project description:Lean or obese C57BL/6JHamSlc-ob/ob (ob/ob) were developed continuous leptin (or vehicle) treatment for 6 weeks. Lung samples were generated from male mice of lean or obese ob/ob on 3 days post infection of mouse-adapted SARS-CoV-2.

2023-05-15 | E-MTAB-12623 | biostudies-arrayexpress

Mouse-adapted SARS-CoV-2 infected Lungs from wild type or genetically obese mice

Project description:Lung samples were generated from male mice of C57BL/6J(B6), C57BL/6JHamSlc-ob/ob (ob/ob) and C57BLKS/J-db/db on 3 days post infection of mouse-adapted SARS-CoV-2

2023-05-15 | E-MTAB-12617 | biostudies-arrayexpress

Mouse-adapted SARS-CoV-2 infected lungs from lean or obese ob/ob mice

Project description:Mouse-adapted SARS-CoV-2 infected lungs from lean or obese ob/ob mice

| PRJEB59989 | ENA

Lung samples from obese mice with or without mouse-adapted SARS-CoV-2 infection

Project description:Lung samples were generated from male mice of C57BL/6JHamSlc-ob/ob (ob/ob) and C57BLKS/J-db/db on 3 days post infection of mouse-adapted SARS-CoV-2 or non-infected condition

2023-05-15 | E-MTAB-12618 | biostudies-arrayexpress

Gene Expression Analysis of Host Immune Responses in CD11b positive cells isolated from lungs of the UV inactivated SARS-CoV-immunized mice following Lethal SARS-CoV Infection

Project description:To better understand the biological pathways by which UV inactivated SARS-CoV-induced pulmonary eosinophilia occurs, we examined global transcriptional changes in macrophages from the lungs of mouse. Female BALB/c mice were used at 21 weeks of age. Mice were subcutaneously immunized with UV inactivated SARS-CoV (UV-V) or UV-V and Toll like receptor (TLR) ligands at 6 and 1 weeks prior to mouse-adapted SARS-CoV (n=6 per group). Mice were intranasally challenged with 1E+6 TCID50 in 30M-NM-<L. MEM was challenged in six mice as control infection. Mice were sacrificed and collected lungs at 1 days after challenge, then CD11b positive cells were isolated from the lungs of these mice. These cells were used for the analysis of microarray.

2014-05-22 | E-GEOD-50855 | biostudies-arrayexpress

Lung samples from obese mice with or without mouse-adapted SARS-CoV-2 infection

Project description:Lung samples from obese mice with or without mouse-adapted SARS-CoV-2 infection

| PRJEB59895 | ENA

Lung samples from SLE model mice with or without mouse-adapted SARS-CoV-2 infection

Project description:Lung samples were generated from female mice of MRL/MpJ-+/+(MpJ) and MRL/MpJ-lpr/lpr (lpr) on 3 days post infection of mouse-adapted SARS-CoV-2 or non-infected condition.

2024-10-01 | E-MTAB-13838 | biostudies-arrayexpress

RNA sequencing of lungs from WT and IFITM3 knockout mouse lungs after SARS-CoV-2 infection

Project description:WT and IFITM3 KO mice were infected with 10^5 TCID50 SARS-CoV-2 MA10 (mouse adapted virus originally generated by the Baric Lab at UNC). 2 days post infection, RNA was extracted from lung tissue using TRIzol. RNA library preparation and sequencing was performed by Genewiz.

2023-01-31 | GSE194062 | GEO

Increased morbidity of obese mice infected with mouse-adapted SARS-CoV-2.

Project description: Not available

| S-EPMC8386345 | biostudies-literature

SARS-CoV-2 mouse adaptation generates a gain of function that causes TNF driven age-dependent severe disease with human correlates

Project description:To dissect the nature of the immune dysregulation induced by SARS-CoV-2 infection in mouse lungs using mouse-adapted strains of the virus. Comparisons were performed using bulk RNA-seq data from mouse (C57BL/6) lung homogenates taken 3 days post-infection with mouse-adapted SARS-CoV-2, both early and late (virulent) passages, or mock-infected mice.

2023-11-09 | GSE217556 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data