Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MMyoDau

ABSTRACT: Myotis daubentonii (Daubenton's bat)

PROVIDER: PRJEB61137 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	ERR11217108_1.fastq.gz	Fastqsanger.gz
	ERR11217108_2.fastq.gz	Fastqsanger.gz
	ERR11217109_1.fastq.gz	Fastqsanger.gz
	ERR11217109_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 19

Similar Datasets

insect metagenome

Project description:Prey selection of the bat Myotis daubentonii

| PRJNA300340 | ENA

mMyoDau2

Project description:Myotis daubentonii (Daubenton's bat) genome assembly, mMyoDau2

| PRJEB65246 | ENA

mMyoDau

Project description:Myotis daubentonii (Daubenton's bat), genomic and transcriptomic data

| PRJEB61136 | ENA

myotis bat morbillivirus

Project description:We report myotis bat morbillivirus sequence indentification from myotis riparius

2021-07-31 | GSE166170 | GEO

mMyoDau2 alternate haplotype

Project description:Myotis daubentonii (Daubenton's bat) genome assembly, mMyoDau2, alternate haplotype

| PRJEB65247 | ENA

Myotis daubentonii

Project description:Myotis daubentonii overview

| PRJNA564358 | ENA

Transcriptional dynamics of transposable elements in the type I IFN response in Myotis lucifugus cells (CUT&RUN)

Project description:Bats are a major reservoir of zoonotic viruses, and there has been growing interest in characterizing bat-specific features of innate immunity and inflammation. Recent studies have revealed bat-specific adaptations affecting interferon (IFN) signaling and IFN-stimulated genes (ISGs), but we still have a limited understanding of the genetic mechanisms that have shaped the evolution of bat immunity. Here we investigated the transcriptional and epigenetic dynamics of transposable elements (TEs) during the type I IFN response in little brown bat (Myotis lucifugus) primary embryonic fibroblast cells, using RNA-seq and CUT&RUN. We found multiple bat-specific TEs that undergo both locus-specific and family-level transcriptional upregulation in response to IFN. Our transcriptome reassembly identified multiple ISGs that have acquired novel exons from bat-specific TEs, including NRLC5, SLNF5 and a previously unannotated isoform of the IFITM2 gene. We also identified examples of TE-derived regulatory elements, but did not find strong evidence supporting genome-wide epigenetic activation of TEs in response to IFN. Collectively, our study uncovers numerous TE-derived transcripts, proteins, and alternative isoforms that are induced by IFN in Myotis lucifugus cells, highlighting potential candidate loci that contribute to bat-specific immune function.

2022-04-21 | GSE200831 | GEO

Project description:Bat (Myotis myotis) skin fibroblast

| PRJNA415775 | ENA

Transcriptional dynamics of transposable elements in the type I IFN response in Myotis lucifugus cells (RNA-Seq)

2022-04-21 | GSE200832 | GEO

myotis bat morbillivirus

Project description:myotis bat morbillivirus

| PRJNA699534 | ENA