Project description:Biological triplicates of the 4 stages of eosinophil maturation (from I to IV) were sorted via FACS from human bone marrow and analyzed by RNA-seq to allow studying transcriptomic changes along human eosinophil development.
Project description:Biological triplicates of the 4 stages of eosinophil maturation (from I to IV) were sorted via FACS from the bone marrow of mice in the steady state and in IL-33 induced eosinophilia, allowing to study the transcriptional changes occurring during eosinophil maturation in both conditions.
Project description:We took a global approach to identify the genome-wide transcriptome in native murine eosinophils sorted from the bone marrow of C57BL6J mice at homeostasis.
Project description:This study aimed to investigate the effect of IL-33 in eosinophil in the context of arthritis. To address this, bone marrow derived eosinophils were generated and treated with or without IL-33 for 3 hours. Then total RNAs were subjected to the study.
Project description:RNA-seq of the 4 eosinophil maturation stages in the murine bone marrow during Interleukin-33 induced eosinophilia combined with Anti-IL5 or Control isotype injections.
Project description:RNA-seq of the 4 stages of maturation of eosinophils in the murine bone marrow in the steady state and in Interleukin-33- induced eosinophilia.