Project description:New Caledonia’s enigmatic terrestrial diving beetle Typhlodessus monteithi is a highly derived species of Australian Paroster revealed by whole genome sequencing
Project description:Malassezia is considered to be involved in the pathogenesis of atopic dermatitis (AD). However, the specific role of Malassezia in the pathogenesis of AD is still unclear, as the current studies mainly focus on the mechanism of immune responses induced by it. The studies on specific molecular mechanisms are insufficient, which is unfavorable to in-depth understand the influence of Malassezia on host immune cells. We used microarrays to detect the influence of M. globosa on the gene expression of peripheral blood mononuclear cells (PBMCs) from AD patients.
Project description:In this work, we have used deep sequencing to study the viral small RNA (vsiRNA) populations from different mycoviruses infecting field isolates of Botrytis spp. The mycoviruses under study belong to different genera and species and have different type of genome (dsRNA, (+)ssRNA, and (-)ssRNA). In general, vsiRNAs derived from mycoviruses are mostly of 21, 20 and 22 nucleotides in length, possess sense or antisense orientation either in a similar ratio or with a predominance of sense polarity depending on the virus species, have predominantly U at their 5' end, and are unevenly distributed along the viral genome showing conspicuous hotspots of vsiRNA accumulation. These characteristics reveal striking concomitances with vsiRNAs produced by plant viruses suggesting similar pathways of viral targeting in plants and fungi
