Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

BPsiEch

ABSTRACT: Psittacula echo (Mauritius parakeet)

PROVIDER: PRJEB64768 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	ERR11814144_1.fastq.gz	Fastqsanger.gz
	ERR11814144_2.fastq.gz	Fastqsanger.gz
	ERR11814145_1.fastq.gz	Fastqsanger.gz
	ERR11814145_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 11

Similar Datasets

bPsiEch3

Project description:Psittacula echo (Mauritius parakeet) genome assembly, bPsiEch3

| PRJEB65273 | ENA

bPsiEch

Project description:Psittacula echo (Mauritius parakeet), genomic and transcriptomic data

| PRJEB64767 | ENA

bPsiEch3 alternate haplotype

Project description:Psittacula echo (Mauritius parakeet) genome assembly, bPsiEch3, alternate haplotype

| PRJEB65272 | ENA

Psittacula echo

Project description:Psittacula echo overview

| PRJNA994645 | ENA

Psittacula echo isolate:PE

Project description:Psittacula Echo - COI Gene Sequences

| PRJNA994424 | ENA

Psittacula echo

Project description:Psittacula echo Genome sequencing and assembly

| PRJNA703618 | ENA

Monk Parakeet Microsatellites

Project description:Microsatellite characterisation and sex-typing in two invasive parakeet species, the monk parakeet, Myiopsitta monachus, and the ring-necked parakeet, Psittacula krameri.

| PRJEB30912 | ENA

Interrogation of the Dynamic Properties of Higher-Order Heterochromatin Using CRISPR/dCas9

Project description:Eukaryotic chromosomes feature large regions of compact, transcriptionally-repressed heterochromatin hallmarked by the presence of Heterochromatin Protein 1 (HP1) family members. HP1 proteins play multi-faceted roles in directly shaping the properties of heterochromatin, and in vivo , HP1 tethering to individual gene promoters leads to epigenetic modifications and gene silencing. However, emergent properties of HP1 at supranucleosomal scales have been difficult to study in cells due to a lack of appropriate tools. Here, we develop CRISPR-Engineered Chromatin Organization (EChO), a novel approach for combining live cell CRISPR-based imaging with inducible and reversible large-scale recruitment of heterochromatin components to native chromatin in human cells. Using CRISPR-EChO, we demonstrate that human HP1α binding across tens of kilobases of genomic DNA leads to formation of novel contacts with other heterochromatin regions and reversibly compacts chromatin from a diffuse to condensed state. The condensed chromatin state exhibits delayed disassembly kinetics and represses transcription across over 600 kilobases. Collectively, these findings support a polymer model of HP1α-mediated chromatin regulation and highlight the utility of CRISPR-EChO in studying and manipulating supranucleosomal chromatin organization in living cells.

2021-05-26 | GSE175500 | GEO

Homo sapiens

Project description:Echo HeLa Dilutions

| PRJNA516235 | ENA

Psittacula caniceps

Project description:Psittacula caniceps

| PRJNA530019 | ENA