Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Cynomolgus macaque Catechol-O-methyltransferase (COMT) Val158Met encoded polymorphism

ABSTRACT: Cynomolgus macaque COMT Val158Met encoded polymorphism

PROVIDER: PRJEB65031 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Atlas of Cynomolgus Macaque Hematopoiesis

Project description:Self-renewal and differentiation are inherent properties of hematopoietic stem cells that are necessary to support hematopoiesis. However, the underlying mechanisms, especially in human, remain unclear. Here, using the cynomolgus macaque as a surrogate model, we develop a new gating strategy to isolate with high purity transplantable cynomolgus HSCs and generated a single-cell transcriptomic map of cynomolgus HSCs and progenitor cells, that covers the gestational period not analyzed in human. We show that hematopoietic cells from the late-1st to early-3rd trimester fetal liver and late-2nd trimester and thereafter bone marrow has repopulating potential, closely mimicking humans. Unexpectedly however, we found unlike in human, cynomolgus HSCs express CD38 but not CD33, indicating that these cellular counterparts are molecularly distinct. Our transcriptomic analysis reveals the presence of a direct differentiation pathway from HSCs to megakaryocyte lineages, lineage-primed multipotent progenitors and also identified putative HSC surface markers. Taken together, our comprehensive dataset highlights not only the utility of cynomolgus monkeys as model systems to study hematopoiesis but also their potential for translational applications.

2024-04-26 | GSE262140 | GEO

Phased cynomolgus macaque assembly

Project description:High-quality phased assembly of the cynomolgus macaque genome

| PRJEB37906 | ENA

cynomolgus macaque miRNAs

Project description:Characterization of miRNAs distribution in cynomolgus macaque genome using small RNA sequencing

| PRJEB32837 | ENA

mitochondrial 12S rRNA sequences Cynomolgus macaque

Project description:mitochondrial 12S rRNA sequences Cynomolgus macaque

| PRJEB49348 | ENA

Infinium Monkeys: Infinium 450K array for the Cynomolgus macaque (Macaca fascicularis) (methylation array)

Project description:Infinium 450K is a hybridization array designed for the human genome, but the relative conservation between the macaque and human genomes makes its use in macaques feasible. We used the Infinium450K array to assay twelve Cynomolgus macaque muscle biopsies and compared it to Reduced Representation Bisulphite Sequencing (RRBS) data generated on the same samples.

2014-06-05 | GSE52944 | GEO

Infinium Monkeys: Infinium 450K array for the Cynomolgus macaque (Macaca fascicularis) RRBS-seq

2014-06-05 | GSE53593 | GEO

Infinium Monkeys: Infinium 450K array for the Cynomolgus macaque (Macaca fascicularis) (methylation array)

2014-06-05 | E-GEOD-52944 | biostudies-arrayexpress

Infinium Monkeys: Infinium 450K array for the Cynomolgus macaque (Macaca fascicularis) RRBS-seq

2014-06-05 | E-GEOD-53593 | biostudies-arrayexpress

cynomolgus macaque miRNAs

Project description:Distribution characterization of conserved miRNAs in cynomolgus macaque genome using small RNA sequencing and homology searching

| PRJEB36250 | ENA

cynomolgus macaque miRNAs

Project description:Distribution characterization of conserved miRNAs in cynomolgus macaque genome using small RNA sequencing and homology searching

| PRJEB36952 | ENA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data