Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

GfInoCfpo

ABSTRACT: Inocybe cf. posterula

PROVIDER: PRJEB65404 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR11892485.fastq.gz	Fastqsanger.gz
	ERR11904128_1.fastq.gz	Fastqsanger.gz
	ERR11904128_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 3 of 3

Similar Datasets

gfInoCfpo

Project description:Inocybe cf. posterula, genomic and transcriptomic data

| PRJEB65403 | ENA

gfInoTigr

Project description:Inocybe tigrina

| PRJEB60657 | ENA

gfInoGrao

Project description:Inocybe grammopodia

| PRJEB60655 | ENA

gfInoObsi

Project description:Inocybe obscuroides

| PRJEB65398 | ENA

Inocybe tigrina

Project description:Inocybe tigrina overview

| PRJNA1152689 | ENA

miR-146a is overexpressed and contributes to dampen IL-6 production in cystic fibrosis macrophages

Project description:In this study, we investigated whether miRNA deregulation might underlie the functional abnormalities of cystic fibrosis (CF) macrophages. To this aim we performed miRNA profiling in macrophages from CF and non-CF macrophages. This led to the identification of a panel of differentially expressed miRNAs in CF macrophages compared to non-CF cells.

2020-04-14 | GSE134702 | GEO

gfInoFrau

Project description:Inocybe fraudans (pear fibrecap)

| PRJEB65410 | ENA

gfInoPeti

Project description:Inocybe petiginosa (scurfy fibrecap)

| PRJEB75066 | ENA

gfInoAste

Project description:Inocybe asterospora (star fibrecap)

| PRJEB84083 | ENA

miRNA repertoires of ex-vivo bronchial, nasal, and polyps cells cultured from healthy and CF donors

Project description:Cystic fibrosis (CF), a genetic disorder, is characterized by chronic lung disease. Small non-coding RNAs are key regulators of gene expression and participate in various processes, which are dysregulated in CF; however, they remain poorly studied. Here, we determined the complete microRNAs (miRNAs) expression pattern in three CF ex-vivo models. The miRNA profiles of air-liquid interface cultures of airway epithelia (bronchi, nasal cells, and nasal polyps) samples from patients with CF and non-CF controls were obtained by deep sequencing. Compared with non-CF controls, several miRNAs were deregulated in CF samples, for instance miR-181a-5p and the miR-449 family were upregulated. Moreover, mature miRNAs often showed variations (i.e., isomiRs) relative to their reference sequence, such as miR-101, suggesting that miRNAs consist of heterogeneous repertoires of multiple isoforms with different effects on gene expression. Analysis of miR-181a-5p and miR-101-3p roles indicated that they regulate the expression of WISP1, a key component of cell proliferation/migration programs. We showed that miR-101 and miR-181a-5p participated in aberrant recapitulation of wound healing programs by controlling WISP1 mRNA and protein level. Our miRNA expression data bring new insights into CF physiopathology and define new potential therapeutic targets in CF

2020-10-21 | GSE159708 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data