US Sewage Project
Ontology highlight
ABSTRACT:
PROVIDER: PRJEB66906 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| ERR12350100_1.fastq.gz | Fastqsanger.gz | |||
| ERR12350100_2.fastq.gz | Fastqsanger.gz | |||
| ERR12350101_1.fastq.gz | Fastqsanger.gz | |||
| ERR12350101_2.fastq.gz | Fastqsanger.gz | |||
| ERR12350102_1.fastq.gz | Fastqsanger.gz |
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E-mail: jbassaga@vt.edu
This model represents the interaction between Cdiff, miRNA146b, NCOA4, PPARg, IL10 and IL17. Simulation studies show an aberrant expression of miRNA146b with increasing concentrations of Cdiff over time, which results in decreased PPARg activation due to NCOA4 inhibition. As a final result, PPARg is unable to modulate effector and regulatory responses, since results show an upregulation of IL17 expression and downregulation of IL10 production.
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