Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genomic surveillance of Vibrio sp

ABSTRACT: Genomic surveillance of Vibrio sp

PROVIDER: PRJEB68309 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR12252300_1.fastq.gz	Fastqsanger.gz
	ERR12252300_2.fastq.gz	Fastqsanger.gz
	ERR12252301_1.fastq.gz	Fastqsanger.gz
	ERR12252301_2.fastq.gz	Fastqsanger.gz
	ERR12252302_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 62

Similar Datasets

Genomic surveillance of Vibrio cholerae infections in Austria

Project description:Genomic surveillance of Vibrio cholerae infections in Austria

| PRJEB68166 | ENA

Surveillance Vibrio cholerae

Project description:Surveillance Vibrio cholerae

| PRJEB67966 | ENA

Genomic Surveillance

Project description:Isolates obtained from Hospital Genomic Surveillance

| PRJEB83276 | ENA

Genomic diversity of Vibrio cholerae

Project description:Genomic surveillance of Vibrio cholerae infections

| PRJEB61542 | ENA

Chitin degradation by Vibrio sp 1A01

Project description:Proteomes of Vibrio sp. 1A01 exponentially growing on various carbon sources as well as on chitin. Chitin samples contain planktonic cells, particle-associated proteins and excreted proteins.

2022-05-19 | MSV000089499 | MassIVE

Transcriptomic analysis of Vibrio sp. dhg in different sugar media.

Project description:Brown macroalgae holds an enormous potential as a future feedstock because it rapidly forms large biomasses and has high carbohydrate content (35% of its dry weight consists of alginate and mannitol). However, utilization of brown macroalgae by conventional microbial platforms (e.g., Escherichia coli and Saccharomyces cerevisiae) has been limited due to the inability of these platforms to metabolize alginate. Although recent studies engineered them to utilize alginate, their growth rates and metabolic activities are still too low for industrial applications, likely due to the unoptimized expression of multiple xenogeneic genes. Here, we isolated Vibrio sp. dhg, a novel, fast-growing bacterium that has been naturally evolved for efficient alginate assimilation (growth rate = 0.98 h-1). Especially, both the growth rate and sugar uptake rate of V. sp. dhg are substantially higher than the rates of E. coli for most biomass-derivable sugars. Based on our systematic characterization of its metabolism and gene expression architecture, we were able to develop a genetic toolbox for its engineering. By using this microorganism, we successfully demonstrated its ability to produce a broad spectrum of chemicals from alginate-mannitol mixtures with high productivities (1.1 g ethanol/L/h, 1.3 g 2,3-butanediol and acetoin/L/h, and 0.69 mg lycopene/L/h). Collectively, the V. sp. dhg strain is a powerful platform for the conversion of brown macroalgae sugars whose usage will dramatically accelerate the production of value-added biochemicals in the future.

2019-05-02 | GSE119357 | GEO

Project description:WTCCC2 project Schizophrenia (SP) samples

| EGAD00010000262 | EGA

Genomic surveillance of Salmonella Typhi

Project description:Genomic surveillance of Salmonella Typhi using ONT platform

| PRJEB60768 | ENA

Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages [ChIP-seq]

Project description:Macrophages play fundamental roles in regulation of inflammatory responses to pathogens, resolution of inflammation and tissue repair, and maintenance of tissue homeostasis. The long (L) and short (S) isoforms of SP-R210/MYO18A, a macrophage receptor for surfactant protein A (SP-A) and C1q, regulate basal and inflammatory macrophage phenotype at multiple gene expression, translational, and subcellular levels in addition to their SP-A and C1q-mediated functions; disruption of L renders macrophages hyper-inflammatory, although the underlying mechanism had previously been unexplored. We questioned whether disruption of the L isoform would alter the global genomic responses. RNA sequencing analysis of SP-R210L(DN) macrophages revealed basal and influenza induced upregulation of genes associated with inflammatory pathways, including TLR, RIG-I, NOD, and cytoplasmic DNA signaling, whereas knockdown of both SP-R210 isoforms (L and S) only resulted in increased RIG-I and NOD signaling. Chromatin immunoprecipitation sequencing (ChIP-seq) analysis showed increased genome-wide deposition of the pioneer transcription factor PU.1 in SP-R210L(DN) compared to WT cells. ChIP-seq analysis of histone H3 methylation showed alterations in both repressive (H3K9me3 and H3K27me3) and transcriptionally active (H3K9me3) histone marks. Influenza A virus (IAV) infection, which stimulates an array of cytosolic and TLR-mediated antiviral mechanisms, resulted in differential redistribution between proximal promoter and distal sites and decoupling of PU.1 binding from Toll-like receptor regulated gene promoters in SP-R210L(DN) cells. Our findings suggest that SP-R210L-deficient macrophages are poised with an open PU.1-primed chromatin conformation to rapidly respond to inflammatory and metabolic stimuli.

2020-12-31 | GSE164034 | GEO

SARS-CoV-2 Genomic Surveillance in Greece

Project description:SARS-CoV-2 Genomic Surveillance in Greece

| PRJEB43435 | ENA