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IcTenMoli

ABSTRACT: Tenebrio molitor (yellow mealworm), genomic and transcriptomic data

PROVIDER: PRJEB70752 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR12342500_1.fastq.gz	Fastqsanger.gz
	ERR12342500_2.fastq.gz	Fastqsanger.gz
	ERR12340106.fastq.gz	Fastqsanger.gz
	ERR12342499_1.fastq.gz	Fastqsanger.gz
	ERR12342499_2.fastq.gz	Fastqsanger.gz

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icTenMoli

Project description:Tenebrio molitor (yellow mealworm)

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Project description:Tenebrio molitor (yellow mealworm) genome assembly, icTenMoli1, alternate haplotype

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Project description:Gut microbiome of yellow mealworm (Tenebrio molitor, Coleoptera: Tenebrionidae) larvae

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Project description:Gut microbiome of yellow mealworm (Tenebrio molitor, Coleoptera: Tenebrionidae) larvae

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Serum metabolomics and proteomics to study the antihyperten-2 sive effect of Tenebrio molitor extracts

Project description:This study aimed at integrating metabolomics and proteomics data for a comprehensive view of the molecular targets of intervention of protein extracts from Tenebrio molitor in treating hypertension. Serum samples from spontaneously hypertensive rats and Wistar Kyoto rats were analyzed using a quantitative metabolomics and label-free proteomics approach based on liquid chromatography coupled with high resolution mass spectrometry (LC-HRMS). Among deregulated metabolites and proteins in hypertensive rats, we found 15 metabolites and 17 proteins that were restored by supplementation with Tenebrio molitor protein extract. The combination of metabolomics and proteomics provided useful data to uncover the molecular targets of intervention and the underlying functional mechanism of Tenebrio molitor protein extract in an animal model such as spontaneously hypertensive rats. The results suggested that Tenebrio molitor supplementation could effectively treat hypertension, partially by regulating proteins and molecules mainly involved in biological pathways associated to angiotensinogen-angiotensin, Serin protease inhibitors, kallikrein–kinin, reactive oxygen scavenging, and lipid peroxidation.

2022-10-13 | PXD034456 | Pride

Nutrigenomics in Animal Feeding: Digital Gene Expression Analysis in Poultry Fed Tenebrio molitor Larvae Meal

Project description:The purpose of this study was to investigate the effects of high levels of Tenebrio molitor dietary inclusion (15%) on molecular mechanisms that influence poultry health in a broiler chicken diet.

2022-02-28 | GSE197444 | GEO

Dissecting the molecular mechanisms of mother-to-egg immune protection in the mealworm beetle Tenebrio molitor

Project description:In a number of species, individuals exposed to pathogens can mount an immune response and transmit this immunological experience to their offspring, thereby protecting them against persistent threats. Such vertical transfer of immunity, named trans-generational immune priming (TGIP), has been described in both vertebrates and invertebrates. Although increasingly studied during the last decade, the mechanisms underlying TGIP in invertebrates are still elusive, especially those protecting the earliest offspring life stage, i.e. the embryo developing in the egg. In the present study, we took the mealworm beetle Tenebrio molitor as a biological model, and combined different proteomic and transcriptomic approaches to determine whether mothers transfer a “signal” (such as fragments of infecting bacteria), mRNA and/or protein/peptide effectors to protect their eggs against two natural bacterial pathogens, namely the Gram-positive Bacillus thuringiensis (Bt) and the Gram-negative Serratia entomophila (Se). We demonstrated that eggs are mainly protected by an active direct transfer of a restricted number of immune proteins and of antimicrobial peptides. In contrast, the present data clearly reject the involvement of mRNA transfer while the transmission of a “signal”, if it happens, is marginal and only occurs within 24h after maternal exposure to bacteria. This work exemplifies the power of combining global multidisciplinary approaches to disentangle the different scenarios of a complex trait, providing a comprehensive characterization of TGIP mechanisms in T. molitor. It also paves the way for future alike studies focusing on TGIP in a wide range of invertebrates and vertebrates to identify additional candidates that could be specific to TGIP and to investigate whether the TGIP mechanisms found herein are specific or common to all insect species.

2020-10-08 | PXD018772 | Pride

Bacterial metataxonomic 16S rRNA from Caecal samples of Chickens Fed Diets including Yellow Mealworm (Tenebrio molitor, L.)

Project description:Bacterial metataxonomic 16S rRNA from Caecal samples of Chickens Fed Diets including Yellow Mealworm (Tenebrio molitor, L.)

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Project description:Effects of yellow mealworm (Tenebrio molitor) meal replacing soybean meal on the intestinal health of Nile tilapia

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