Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Comparison between healthy individuals and Alzheimer's disease patients with covid

ABSTRACT: Comparison between healthy individuals and Alzheimer's disease patients with covid

PROVIDER: PRJEB72710 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Comparison between healthy individuals and Alzheimer's disease patients with covid

Project description:The goal of the experiment was to determine whether monocytes from Alzheimer's disease patients with covid had differentially expressed genes when compared to health individuals.

2024-02-28 | E-MTAB-13809 | biostudies-arrayexpress

Single Cell Multiomics of Healthy, COVID-19 positive and Recovered Individuals

Project description:Single Cell Multiomics of Healthy, COVID-19 positive and Recovered Individuals

| PRJNA828282 | ENA

Trancriptome analysis of peripheral leukocytes from SARS-CoV-2 infected patients and healthy uninfected individuals during the first wave of COVID-19 pandemic in Brazil

Project description:To evaluate the gene expression profiling of peripheral leukocytes in different outcomes of SARS-CoV-2 infections, whole blood samples were collected from individuals with positive SARS-CoV-2 nasopharyngeal swab by RT-PCR (54 patients) and healthy uninfected individuals (12 volunteers). Infected patients were classified into mild, moderate, severe and critical groups according to a modified statement in the Novel Coronavirus Pneumonia Diagnosis and Treatment Guideline. Blood were collected into EDTA tubes and the buffy coat samples were stored in TRIzol reagent at -80 °C until use for RNA extraction. Affymetrix Clariom S array was used to perform the high-throughput gene expression profiling. Microarray analyses were performed using APT Affymetrix software, R packages and Bioconductor libraries. This systemic view of SARS-CoV-2 infections through blood transcriptomics will foster the understanding about molecular mechanisms and immunopathological processes involved in COVID-19 disease and its different outcomes.

2022-04-29 | E-MTAB-11240 | biostudies-arrayexpress

Comparison of cortisol metrics and total RNA profiles from Healthy Individuals

Project description:The study seeks to identify transcripts whose expression levels are significantly correlated with bedtime and awakening cortisol levels in healthy individuals.

2020-07-31 | GSE134637 | GEO

Whole transcriptome sequencing from covid-19 and control lung biopsies

Project description:Whole transcriptome analysis performed on lung samples from dead covid-19 patients and healthy non-covid-19 individuals of multiple age groups.

2022-05-31 | GSE183533 | GEO

Non-demented individuals with intermediate Alzheimer's neuropathologies - neuronal expression (6 regions)

Project description:Layer II stellate neurons (entorhinal cortex) and layer III cortical neurons (hippocampus CA1, middle temporal gyrus, posterior cingulate, superior frontal gyrus, primary visual cortex) were gene expression profiled. Brain regions are from non-demented individuals with intermediate Alzheimer's disease neuropathologies Keywords: neuronal gene expression profiling

2007-12-05 | GSE9770 | GEO

Transcriptional Differences Between COVID-19 and Sepsis

Project description:Although some studies reported the comprehensive mRNA expression analysis of coronavirus disease 2019 (COVID-19) using blood samples to understand its pathogenesis, the characteristics of RNA expression in COVID-19 and sepsis have not been compared. We compared the transcriptome expression of whole blood samples from patients with COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and patients with sepsis caused by other bacteria who entered the intensive care unit to clarify the COVID-19-specific RNA expression and understand its pathogenesis. Transcriptomes related to mitochondria were upregulated in COVID-19, whereas those related to neutrophils were upregulated in sepsis. However, the transcriptomes related to neutrophils were upregulated in both COVID-19 and sepsis compared to in healthy controls, whereas the mitochondrial transcriptomes were upregulated in COVID-19 and downregulated in sepsis compared to in healthy controls. Moreover, sepsis showed sub-optimal intrinsic apoptotic features compared with COVID-19. The transcriptome expression of COVID-19 has been examined in vitro but has not been widely validated using human specimens. This study improves the understanding of the pathogenesis of COVID-19 and can contribute to the development of treatments.

2022-11-29 | GSE199816 | GEO

Comparison of peripheral blood leucocyte subsets in healthy individuals

Project description:CD4+ T cells, CD8+ T cells, CD14+ monocytes, and CD16+ neutrophils from the peripheral blood of 5 healthy individuals were isolated and their ex vivo transcriptomic profiles measured.

2016-06-23 | E-MTAB-4887 | biostudies-arrayexpress

Whole blood transcriptome from Covid-19 patients in India

Project description:High throughput sequencing is performed on mRNA isolated from whole blood of adult Covid-19 patients, bacterial coinfection with Covid-19 and healthy controls in a South Indian cohort. Samples were collected from individuals at the time of hospitalization or visit to clinic. The Covid-19 samples are categorized by severeity.

2022-02-22 | GSE196822 | GEO

Comparative analysis of gene expression between PBMCs from TB patients and healthy individuals.

Project description:Total RNA from PBMCs isolated from TB patients and healthy individuals was subjected to RNASeq analysis. The samples among two groups were compared to analyze differentially expressed genes.

2020-12-31 | GSE148171 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data