Project description:Selective Whole Genome Amplification of Plasmodium malariae DNA from clinical samples reveals high genetic diversity and population structure of this neglected malaria parasite
| PRJEB33837 | ENA
Project description:Hybrid capture sequencing of Plasmodium malariae
Project description:S. meliloti strains with a bi- and monopartite genome configuration were constructed by consecutive Cre/lox-mediated site-specific fusions of the secondary replicons. Beside the correct genomic arrangements, these strains and precursors were tested for variations in the nucleotide sequence. Futher, a marker fequency analysis was performed to test if replication is initiated at all origins and to determine the replication termination regions of the triple replicon fusion molecule. To gain the sequence data for these analyses, respective strains were applied to whole genome sequencing using an Illumina MiSeq-System and Oxford Nanopore (MinION) sequencing technology.