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DaCheTaga

ABSTRACT: Cheirolophus tagananensis (Herba de Sant Segimon)

PROVIDER: PRJEB76612 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	ERR13301104_1.fastq.gz	Fastqsanger.gz
	ERR13301104_2.fastq.gz	Fastqsanger.gz
	ERR13649987.fastq.gz	Fastqsanger.gz
	ERR13999107_1.fastq.gz	Fastqsanger.gz

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daCheTaga

Project description:Cheirolophus tagananensis (Herba de Sant Segimon), genomic and transcriptomic data

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Project description:A microarray analysis was conducted using the brain, heart, and liver tissues of mouse orally administrated aqueous extracts of Ephedra herba, in which the expression level of many genes were altered depending on the duration of treatment time. Aqueous extracts of Ephedra herba were administered orally for 1 hr, 6 hrs, 12 hrs, 24 hrs, 3 days, 5 days and 10 days on mice.

2010-06-24 | E-GEOD-20084 | biostudies-arrayexpress

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Project description:A microarray analysis was conducted using the brain tissue of mouse orally administrated aqueous extracts of Ephedra herba, in which the expression level of many genes were altered depending on the duration of treatment time. In particular, temporal changes in the expressions of genes can be classified into two major reciprocal patterns. Aqueous extracts of Ephedra herba were administered orally at dosage of 50 or 1,250 mg/kg once daily for 1, 3 and 10 consecutive days on mice. Expression level of genes from brain tissue was compared to that from untreated control mice.

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A domesticated Harbinger transposase forms a complex with HDA6 and promotes histone H3 deacetylation at genes but not TEs in Arabidopsis

Project description:In eukaryotes, histone acetylation is a major modification on histone N-terminal tails that is tightly connected to transcriptional activation. HDA6 is a histone deacetylase involved in the transcriptional regulation of genes and transposable elements (TEs) in Arabidopsis thaliana. HDA6 has been shown to participate in several complexes in plants, including a conserved SIN3 complex. Here, we uncover a novel protein complex containing HDA6, several Harbinger transposon-derived proteins (HHP1, SANT1, SANT2, SANT3, and SANT4), and MBD domain-containing proteins (MBD1, MBD2, and MBD4). We show that mutations of all four SANT genes in the sant-null mutant cause increased expression of the flowering repressors FLC, MAF4, and MAF5, resulting in a late flowering phenotype. Transcriptome deep sequencing reveals that while the SANT proteins and HDA6 regulate the expression of largely overlapping sets of genes, TE silencing is unaffected in sant-null mutants. Our global histone H3 acetylation profiling shows that SANT proteins and HDA6 modulate gene expression through deacetylation. Collectively, our findings suggest that Harbinger transposon-derived SANT domain-containing proteins are required for histone deacetylation and flowering time control in plants.

2021-05-10 | GSE167288 | GEO

Temporal gene expression by Ephedra herba in brain, heart and liver of mouse

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Reciprocal regulation of genes expression by Ephedra herba in mouse brain

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Project description:Transcriptomic study of Taxilli Herba

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Zebrafish embryos exposed to the model hedgehog pathway inhibitor cyclopamine, as well as to the potential hedghog pathway disrupters SANT-2 and GANT-61.

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2011-09-30 | E-GEOD-29357 | biostudies-arrayexpress

Escherichia coli

Project description:Agilent_E. coli O157 response to Chrysanthemum herba

| PRJNA135481 | ENA