Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

LpPoaChai

ABSTRACT: Poa chaixii, genomic and transcriptomic data

PROVIDER: PRJEB77498 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR13363435_1.fastq.gz	Fastqsanger.gz
	ERR13363435_2.fastq.gz	Fastqsanger.gz
	ERR13362655.fastq.gz	Fastqsanger.gz

Items per page:

1 - 3 of 3

Similar Datasets

lpPoaChai

Project description:Poa chaixii

| PRJEB77499 | ENA

Poa chaixii

Project description:Poa chaixii overview

| PRJNA1151806 | ENA

lpPoaChai1 hap1

Project description:Poa chaixii genome assembly, lpPoaChai1 haplotype 1

| PRJEB79011 | ENA

lpPoaChai1 hap2

Project description:Poa chaixii genome assembly, lpPoaChai1 haplotype 2

| PRJEB79010 | ENA

Pregnancy damps thermoregulatory rhythms across timescales through neural estrogen signaling in mice

Project description:Pregnancy is accompanied by reductions in core body temperature (Tc) and its circadian amplitude, changes that are thought to provide fetal thermal stability. In the associated manuscript, we show that pregnancy profoundly reshapes thermoregulatory dynamics across diurnal and ultradian timescales, and identify estrogen receptor alpha (ERα) signaling in the preoptic area (POA) as a central mediator of these effects. During pregnancy, ERα-expressing in neurons of the medial POA (MPO) show enhanced estrogen signaling and hormone-responsive gene expression changes. Silencing ERα neurons or selectively deleting ERα in the POA attenuates pregnancy-induced decreases in Tc and its rhythmicity, leading to alterations in gestational length and/or birth weight. Together, these findings demonstrate that ERα signaling within the POA coordinates adaptive remodeling of thermoregulatory rhythms during pregnancy, with direct consequences on fetal outcomes. Here, we share transcriptomic data from ERα-expressing neurons in the MPO from non-pregnant and late pregnant mice.

2026-09-04 | GSE346233 | GEO

DNMT inhibition in the Neonatal Preoptic Area

Project description:PN2 male and female rat pups were treated with vehicle or zebularine. POA RNA was extracted and sequenced to deterime the effects of DNMT inhibition in POA gene expression. Males and Females were treated with either vehicle (0.1% DNMSO in saline) or Zebularine

2015-03-30 | E-GEOD-66203 | biostudies-arrayexpress

Single-cell proteomics analysis of melatonin-treated and MG132-treated in vitro post-ovulatory aged oocytes

Project description:Once ovulated, the oocyte has to be fertilized in a short time window, or it will undergo post-ovulation aging (POA), whose underlying mechanisms are still not elucidated. Here, we optimized single-cell proteomics methods and performed single-cell proteomic and phosphoproteomic analysis of fresh, POA, melatonin-treated and MG132-treated POA oocytes.

2025-05-06 | PXD045614 | Pride

DNMT inhibition in the Neonatal Preoptic Area

Project description:PN2 male and female rat pups were treated with vehicle or zebularine. POA RNA was extracted and sequenced to deterime the effects of DNMT inhibition in POA gene expression.

2015-03-30 | GSE66203 | GEO

Expression profile of adult mouse POA/BF regions

Project description:The adult mammalian brain is composed of distinct regions that have specialized roles. The BF/POA regions are thought to have an important role in the regulation of sleep/wake behavior. However, genetic markers of the responsible cells for the regulation of sleep/wake behavior are largely unknown. To identify the molecular markers of the BF/POA regions, we sampled the BF/POA regions and compared gene expression in the BF/POA regions with those of other brain regions which we previously reported in the BrainStars (B*) project, in which we sampled ~50 small brain regions, including sensory centers and centers for motion, time, memory, fear, and feeding. We sampled each region every 4 hours for 24 hours, and pooled the sample sets for DNA-microarray assays. We then used informatics to identify candidates for genes with high or low expression in the BF/POA regions. We used our findings to develop an integrated database (http://poabf.brainstars.org/) for exploring genome-wide expression in the adult mouse brain including the BF/POA regions.

2018-08-17 | GSE107500 | GEO

RNASeq of cold-sensitive and cold-insensitive neurons from the pre-optic area of hypothalamus of mice

Project description:The preoptic area of the hypothalamus (POA) contains intrinsically warm and cold-sensitive neurons, which are thought to be critically involved in mammalian thermoregulation. However, the precise physiological roles and the molecular markers of the cold-sensitive POA neurons have not been determined yet. Here, we tackle this problem by performing calcium-imaging guided separation and collection of cold-sensitive and cold-insensitive dissociated neurons from the mouse POA, followed by RNASeq and differential transcriptomics of these cell populations.

2020-04-09 | GSE136396 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data