MDR HAIs K.pneumoniae
Ontology highlight
ABSTRACT:
PROVIDER: PRJEB78995 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| ERR13492052_1.fastq.gz | Fastqsanger.gz | |||
| ERR13492052_2.fastq.gz | Fastqsanger.gz | |||
| ERR13492053_1.fastq.gz | Fastqsanger.gz | |||
| ERR13492053_2.fastq.gz | Fastqsanger.gz | |||
| ERR13492054_1.fastq.gz | Fastqsanger.gz |
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Project description:Liao2011 - Genome-scale metabolic
reconstruction of Klebsiella pneumoniae (iYL1228)
This model is described in the article:
An experimentally validated
genome-scale metabolic reconstruction of Klebsiella pneumoniae
MGH 78578, iYL1228.
Liao YC, Huang TW, Chen FC,
Charusanti P, Hong JS, Chang HY, Tsai SF, Palsson BO, Hsiung
CA.
J. Bacteriol. 2011 Apr; 193(7):
1710-1717
Abstract:
Klebsiella pneumoniae is a Gram-negative bacterium of the
family Enterobacteriaceae that possesses diverse metabolic
capabilities: many strains are leading causes of
hospital-acquired infections that are often refractory to
multiple antibiotics, yet other strains are metabolically
engineered and used for production of commercially valuable
chemicals. To study its metabolism, we constructed a
genome-scale metabolic model (iYL1228) for strain MGH 78578,
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experimentally determined its ability to grow on a broad range
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assessed the ability of the model to accurately simulate growth
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Furthermore, quantitative comparison of growth rates between
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showed good agreement. The genome-scale metabolic
reconstruction for K. pneumoniae presented here thus provides
an experimentally validated in silico platform for further
studies of this important industrial and biomedical
organism.
This model is hosted on
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and identified by:
MODEL1507180054.
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