Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Staphylococcus epidermis from prosthetic joint infections

PROVIDER: PRJEB87325 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR14759224_1.fastq.gz	Fastqsanger.gz
	ERR14759224_2.fastq.gz	Fastqsanger.gz
	ERR14759225_1.fastq.gz	Fastqsanger.gz
	ERR14759225_2.fastq.gz	Fastqsanger.gz
	ERR14759226_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 106

Similar Datasets

Project description:Staphylococcus saccharolyticus associated with prosthetic joint infections

| PRJNA689124 | ENA

Project description:Cutibacterium acnes isolates from prosthetic joint infections

| PRJNA850913 | ENA

Project description:Genomic characterization and outcome of Prosthetic Joint Infections caused by Staphylococcus aureus

| PRJEB33164 | ENA

Project description:Cutibacterium avidum strains isolated from prosthetic joint infections

| PRJNA729908 | ENA

Project description:Cutibacterium acnes strains isolated from prosthetic joint infections

| PRJNA714802 | ENA

Cutibacterium avidum

Project description:Cutibacterium avidum isolated from prosthetic hip joint infections

| PRJNA1045027 | ENA

Project description:Heterogeneity of Staphylococcus epidermidis in prosthetic joint infections: Time to reevaluate microbiological criteria?

| PRJEB44086 | ENA

Tissue niche influences immune and metabolic profiles to Staphylococcus aureus biofilm

Project description:Infection is a devastating post-surgical complication, often necessitating additional procedures and prolonged antibiotic therapy. This is especially relevant for craniotomy and prosthetic joint infections, both of which are characterized by biofilm formation on the bone or implant surface, respectively, with S. aureus representing a primary cause. The effectiveness of immune responses to these infections is predicated on both host- and pathogen-derived signals in the infection microenvironment. However, the extent to which these signals differ across distinct tissue niches and influence immune function remains relatively unknown. Using mouse models of S. aureus craniotomy and prosthetic joint infection complemented with patient samples from both infectious modalities, we show profound metabolomic, transcriptomic, and functional differences that are dependent on tissue niche. These signatures were both spatially and temporally distinct, differing not only between surgical site infections but evolving over time within a single model. These findings highlight the unique immune attributes of biofilms that are heavily influenced by the local tissue microenvironment, which will likely have important implications when designing therapeutic approaches to target specific infections.

2024-07-08 | GSE252481 | GEO

Project description:Staphylococcus aureus joint infections

| PRJEB22689 | ENA

Project description:Presence of the neonatal Staphylococcus capitis outbreak clone (NRCS-A) in prosthetic joint infections

| PRJEB35698 | ENA