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Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Collaborative Community Networks to Optimize Implementation of Low Barrier COVID-19 Testing Efforts Among Diverse Latinx Populations in Northern California

ABSTRACT: Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Collaborative Community Networks to Optimize Implementation of Low Barrier COVID-19 Testing Efforts Among Diverse Latinx Populations in Northern California

PROVIDER: PRJNA1001571 | ENA |

REPOSITORIES: ENA

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Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Collaborative Community Networks to Optimize Implementation of Low Barrier COVID-19 Testing Efforts Among Diverse Latinx Populations in Northern California

Project description:Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Collaborative Community Networks to Optimize Implementation of Low Barrier COVID-19 Testing Efforts Among Diverse Latinx Populations in Northern California

| PRJNA1001567 | ENA

EFForTs B08 nematode

Project description:EFForTs B08 tropical soil nematodes

| PRJEB49837 | ENA

Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Developing a Realtime Monitoring System and Program to Improve COVID-19 Testing for Latinx Populations

Project description:Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Developing a Realtime Monitoring System and Program to Improve COVID-19 Testing for Latinx Populations

| PRJNA798824 | ENA

Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Developing a Realtime Monitoring System and Program to Improve COVID-19 Testing for Latinx Populations

Project description:Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Developing a Realtime Monitoring System and Program to Improve COVID-19 Testing for Latinx Populations

| PRJNA798823 | ENA

Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Scaling Up SARS-COV-2 Testing to Serve Latinx Communities

Project description:Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Scaling Up SARS-COV-2 Testing to Serve Latinx Communities

| PRJNA759662 | ENA

Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Scaling Up SARS-COV-2 Testing to Serve Latinx Communities

Project description:Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Scaling Up SARS-COV-2 Testing to Serve Latinx Communities

| PRJNA759661 | ENA

Colorectal Screening Strategies in Underserved Populations

Project description:Research efforts are necessary to identify strategies to increase colorectal screening in underserved patient populations. Racial, ethnic minorities and medically underserved individuals continue to experience disparities in colorectal cancer mortality despite the availability of screening tests that can detect tumors early when treatments are most effective.

| 2394515 | ecrin-mdr-crc

Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Enhancing SARS-Co-V-2 Rapid Testing Acceptance in Latinx Communities

Project description:Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Enhancing SARS-Co-V-2 Rapid Testing Acceptance in Latinx Communities

| PRJNA1060413 | ENA

Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Enhancing SARS-Co-V-2 Rapid Testing Acceptance in Latinx Communities

Project description:Rapid Acceleration of Diagnostics - Underserved Populations (RADx-UP): Enhancing SARS-Co-V-2 Rapid Testing Acceptance in Latinx Communities

| PRJNA1060414 | ENA

Pathways for intervention to optimize donor organ quality uncovered: a genome wide gene expression study

Project description:Background: Strategies to improve long term renal allograft survival have been directed to recipient dependent mechanisms of renal allograft injury. In contrast, no such efforts have been made to optimize organ quality in the donor. In order to get insight into the deleterious gene pathways expressed at different time points during deceased kidney transplantation, transcriptomics was performed on kidney biopsies from a large cohort of deceased kidney transplants. Methods: A total of 554 kidney biopsies were taken from living and deceased donor kidneys at donation, after cold ischemia and after reperfusion. Transcriptomics by means of whole genome micro-array analyses followed by functional pathway analyses was performed. Results: Oxidative stress and complement- and coagulation pathways were uncovered as potential pathways for intervention in deceased donors. No genes were found to be differentially expressed between donation and cold ischemia. After reperfusion, pathways related to oxidative stress, NOD-like signalling, MAPK, cytokine-cytokine receptor, complement- and-coagulation and chemokines were enriched in kidneys from deceased organ donors. Pathways related to prolonged and worsening deprivation of oxygen were associated with delayed graft function of DCD grafts. Conclusions: The present study reveals oxidative stress and enrichment of complement and coagulation pathways in deceased donor kidneys. Future intervention therapies to optimize donor organ quality and prolong allograft survival should target oxidative stress and innate immune activation in the donor.

2015-04-02 | GSE43974 | GEO

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