Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Profiling tRNA modifications in Mycobacterium tuberculosis

ABSTRACT: Profiling tRNA modifications in Mycobacterium tuberculosis

PROVIDER: PRJNA1002795 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR25541761.fastq.gz	Fastqsanger.gz
	SRR25541762.fastq.gz	Fastqsanger.gz
	SRR25541763.fastq.gz	Fastqsanger.gz
	SRR25541764.fastq.gz	Fastqsanger.gz
	SRR25541765.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Profiling tRNA modifications in Mycobacterium tuberculosis

Project description:Diverse chemical modifications fine-tune the function and metabolism of tRNA. Although tRNA modification is universal in all kingdoms of life, profiles of modifications, their functions, and physiological roles have not been elucidated in most organisms including the human pathogen, Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis. To identify physiologically important modifications, we surveyed the tRNA of Mtb, using tRNA sequencing (tRNA-seq). Reverse transcription-derived error signatures in tRNA-seq predicted the sites and presence of 9 modifications. Several chemical treatments prior to tRNA-seq expanded the number of predictable modifications. Deletion of Mtb genes encoding two modifying enzymes, TruB and MnmA, eliminated their respective tRNA modifications, validating the presence of modified sites in tRNA species.

2023-08-11 | GSE240200 | GEO

Mycobacterium tuberculosis H37Rv strains: Control vs. Linezolid.

Project description:Transcriptional profiling of Mycobacterium tuberculosis H37Rv strains comparing control DMSO treated strains with Linezolid treated strains. Goal was to determine the effects of Linezolid against Mycobacterium tuberculosis H37Rv strains.

2011-10-11 | GSE32718 | GEO

Mycobacterium tuberculosis H37Rv strains: Control vs. Lupulone

Project description:Transcriptional profiling of Mycobacterium tuberculosis H37Rv strains comparing control DMSO treated strains with Lupulone treated strains. Goal was to determine the effects of Lupulone against Mycobacterium tuberculosis H37Rv strains.

2011-08-30 | GSE31732 | GEO

Mycobacterium tuberculosis: yidC (Rv3921c) induced Vs Control cultures

Project description:Transcriptional profiling of Mycobacterium tuberculosis H37Ra::pTetR-yidC (Test) compared with Mycobacterium tuberculosis H37Ra::pTetR (Control) bacteria after 4 days of treatment with 50ng/ml ATc with shaking at 200rpm at 37°C.

2018-11-28 | GSE110355 | GEO

MntR(Rv2788): a transcriptional regulator that controls manganese homeostasis in Mycobacterium tuberculosis.

Project description:Transcriptional profiling of SirR and manganese regulated expression of genes in Mycobacterium tuberculosis strains comparing high manganese vs. low manganese in Rv (wild type Mycobacterium tuberculosis) and ST70 (mntR mutant strain of Mycobacterium tuberculosis)

2015-12-08 | GSE70812 | GEO

Mycobacterium tuberculosis Persister Stimulon

Project description:Transcriptional profiling of Mycobacterium tuberculosis mc2 7000 surviving 4 days of isoniazid treatment relative to untreated to investigate genes relevant to survival in genotypically isoniazid-sensitive cells

2016-09-23 | GSE86141 | GEO

Mycobacterium tuberculosis clinical isolates in China: extensively drug-resistant tuberculosis vs drug sensitive one

Project description:Transcriptional profiling of mycobacterium tuberculosis clinical isolates in China comparing extensively drug-resistant tuberculosis with drug sensitive one.

2009-04-04 | GSE15540 | GEO

Gene expression based profiling of Mycobacterium tuberculosis infected primary murine osteoclasts.

Project description:Mycobacterium tuberculosis(Mtb) is known to reside in cells of innate immune system- macrophages and dendritic cells. A variety of non -conventional cell typeslike adipocytes, mesenchyal stem cells and osteoclasts can also be infected with Mtb. However, cellular transcriptional adapations enabling survival of Mtb in these cells remain known. We used microarrays to understand global changes in transcriptional profiling during macrophage to osteoclast transition in presence of Mycobacterium tuberculosis.

2016-08-15 | GSE61531 | GEO

Transcriptional Profile of Mycobacterium tuberculosis Colony Morphotype Variants

Project description:Transcriptional profiling of Mycobacterium tuberculosis mc2 7000 spread and raised colony morphotypes

2021-03-03 | GSE89089 | GEO

Transcriptome analysis of Mycobacterium tuberculosis post 24 hours VapC11 overexpression.

Project description:We report the effects of VapC11 overexpression on Mycobacterium tuberculosis H37Rv strain. VapC11 is a tRNase which specifically cleaves tRNA-Leu^CAG (leuT).Cells harbouring either pTetR (Control) or pTetR-vapC11 was used to understand the effect of VapC11 toxin overproduction on cellular transcriptome.

2018-07-11 | GSE116861 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data