Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome profile analyses of head kidney in roach (Rutilus rutilus), common bream (Abramis brama) and their hybrids: does infection by monogenean parasites in freshwater fish reveal differences in fish vigour among parental species and their hybrids?

ABSTRACT: Transcriptome profile analyses of head kidney in roach (Rutilus rutilus), common bream (Abramis brama) and their hybrids: does infection by monogenean parasites in freshwater fish reveal differences in fish vigour among parental species and their hybrids?

PROVIDER: PRJNA1005674 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR25648900_1.fastq.gz	Fastqsanger.gz
	SRR25648900_2.fastq.gz	Fastqsanger.gz
	SRR25648901_1.fastq.gz	Fastqsanger.gz
	SRR25648901_2.fastq.gz	Fastqsanger.gz
	SRR25648902_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 180

Similar Datasets

Transcriptome profile analyses of head kidney in roach (Rutilus rutilus), common bream (Abramis brama) and their hybrids: does infection by monogenean parasites in freshwater fish reveal differences in fish vigour among parental species and their hybrids?

Project description:Hybrid generations usually face either a heterosis advantage or a breakdown that can be expressed by the level of parasite infection in hybrid hosts. Hybrids are less infected by parasites than parental species (especially F1 generations) or more infected than parental species (especially post-F1 generations). We performed the experiment with blood-feeding gill parasite Paradiplozoon homoion (Monogenea) infecting leuciscid species, Abramis brama and Rutilus rutilus, their F1 generation, and two backcross generations. Backcross generations tended to be more parasitized than parental lines and the F1 generation. The number of differentially expressed genes (DEGs) was lower in F1 hybrids and higher in backcross hybrids when compared to each of the parental lines. The main groups of DEGs were shared among lines, however, Abramis brama and Rutilus rutilus differed in some of the top gene ontology (GO) terms. DEG analyses revealed the role of heme binding and erythrocyte differentiation after infection by blood-feeding P. homoion. Two backcross generations shared some of the top GO terms representing mostly downregulated genes associated with P. homoion infection. KEGG analysis revealed the importance of disease-associated pathways. The majority of them were shared by two backcross generations. Our study revealed the most pronounced DEGs associated with monogenean infection in backcross hybrids, potentially explained by hybrid breakdown. The gene expression of F1 hybrids was little affected by P. homoion, suggesting the hybrid advantage.

2023-10-01 | GSE240906 | GEO

Transcriptome Profile Analyses of Head Kidney in Roach (<i>Rutilus rutilus</i>), Common Bream (<i>Abramis brama</i>) and Their Hybrids: Does Infection by Monogenean Parasites in Freshwater Fish Reveal Differences in Fish Vigour among Parental Species and Their Hybrids?

Project description:Hybrid generations usually face either a heterosis advantage or a breakdown, that can be expressed by the level of parasite infection in hybrid hosts. Hybrids are less infected by parasites than parental species (especially F1 generations) or more infected than parental species (especially post-F1 generations). We performed the experiment with blood-feeding gill parasite Paradiplozoon homoion (Monogenea) infecting leuciscid species, Abramis brama and Rutilus rutilus, their F1 generation and two backcross generations. Backcross generations tended to be more parasitized than parental lines and the F1 generation. The number of differentially expressed genes (DEGs) was lower in F1 hybrids and higher in backcross hybrids when compared to each of the parental lines. The main groups of DEGs were shared among lines; however, A. brama and R. rutilus differed in some of the top gene ontology (GO) terms. DEG analyses revealed the role of heme binding and erythrocyte differentiation after infection by blood-feeding P. homoion. Two backcross generations shared some of the top GO terms, representing mostly downregulated genes associated with P. homoion infection. KEGG analysis revealed the importance of disease-associated pathways; the majority of them were shared by two backcross generations. Our study revealed the most pronounced DEGs associated with blood-feeding monogeneans in backcross hybrids, potentially (but not exclusively) explainable by hybrid breakdown. The lower DEGs reported in F1 hybrids being less parasitized than backcross hybrids is in line with the hybrid advantage.

| S-EPMC10525477 | biostudies-literature

Rutilus rutilus

Project description:Rutilus rutilus overview

| PRJNA343566 | ENA

Rutilus rutilus

Project description:Rutilus rutilus alternate pseudohaplotype genome sequencing

| PRJNA768316 | ENA

Rutilus rutilus

Project description:Rutilus rutilus principal pseudohaplotype genome sequencing

| PRJNA768317 | ENA

Rutilus rutilus

Project description:Rutilus rutilus Genome sequencing and assembly