Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Hydra oligactis sterile environment 16S (hydra metagenome / aquatic metagenome)

PROVIDER: PRJNA1007933 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR25742828_1.fastq.gz	Fastqsanger.gz
	SRR25742828_2.fastq.gz	Fastqsanger.gz
	SRR25742829_1.fastq.gz	Fastqsanger.gz
	SRR25742829_2.fastq.gz	Fastqsanger.gz
	SRR25742830_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 124

Similar Datasets

Invasive tumors in Hydra

Project description:The molecular nature of malignant tumors is well studied in vertebrates, while their evolutionary origin remains unknown. In particular, there is no evidence for naturally occurring malignant tumors in pre-bilaterian animals, such as sponges and cnidarians. This is somewhat surprising given that recent computational studies have predicted that all metazoans are prone to develop tumors. Here we provide first evidence for naturally occurring tumors in Hydra oligactis. Histological, cellular and molecular data reveal that these tumors are transplantable and caused by differentiation arrest of female gametes. Growth of tumor cells is independent from the cellular environment. Tumor bearing polyps have significantly reduced fitness. In addition, Hydra tumors show a greatly altered transcriptome that mimics expression shifts in vertebrate cancers. Therefore, this study shows, that invasive tumors have deep roots in animal phylogeny, and that early branching animals may be informative in revealing the fundamental mechanisms of tumorigenesis. We compared four samples of Hydra oligactis tumor-bearing animals to three samples of female polyps undergoing oogenesis and six samples of female asexual control polyps

2014-06-24 | E-GEOD-56287 | biostudies-arrayexpress

Hydra oligactis

Project description:Hydra oligactis overview

| PRJNA242786 | ENA

Project description:Hydra oligactis microbiome

| PRJNA1092055 | ENA

Naturally occurring tumours in the basal metazoan Hydra.

2014-06-24 | GSE56287 | GEO

Project description:Hydra oligactis RNA-Seq

| PRJNA937400 | ENA

Hydra oligactis

Project description:Hydra oligactis and associated bacteria