Project description:To determine the signaling pathway involved in LS-1-2-mediated tumor inhibition, we performed genome-wide gene expression by comparing HCT116 cells with and without LS-1-2treatment.
Project description:cDNA microarray study of X-radiation (XR) sensitive HCT116-CloneK cells 24 hours after XR treatment at 4Gy versus unirradiated HCT116-Clone10 cells. HCT116-Clone10 cells have similar XR response with parental HCT116 cells. Keywords = X-radiation (XR), XR sensitive, colorectal cancer cells, HCT1116 Keywords: repeat sample
Project description:cDNA microarray study of X-radiation (XR) sensitive HCT116-CloneK cells six hours after XR treatment at 4Gy versus unirradiated HCT116-Clone10 cells. HCT116-Clone10 cells have similar XR response with parental HCT116 cells. Keywords = X-radiation (XR), XR sensitive, colorectal cancer cells, HCT1116 Keywords: repeat sample
Project description:cDNA microarray study of X-radiation (XR) sensitive HCT116-CloneK cells 10 minutes after XR treatment at 4Gy versus unirradiated HCT116-Clone10 cells. HCT116-Clone10 cells have similar XR response with parental HCT116 cells. Keywords = X-radiation (XR), XR sensitive, colorectal cancer cells, HCT1116 Keywords: repeat sample
Project description:HCT116 wild type cells express p53. The isogenic HCT116 p53KO cells have the p53 gene knocked out. Cells were treated for 16 hours. Dosages for actinomycin D treatment was 1 nM, 10 nM, and 100 nM. Dosage for nutlin-3 was 4 uM. Keywords: dose response