Project description:HUVEC respond to pro-inflammatory stimuli such as IL-1 by expressing several hundreds of genes including cytokines, chemokines, cell adhesion molecules, and those involved in coagulation, survival/apoptosis, and metabolism. Extract of P. santalinus inhibited the expression of certain genes, while leaving other unaffected; therby a set of responsive and non-responsive genes could be defined, to be further analyzed by bioinformatics.
