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DNA methylome, R-loop and clinical exome profiling of patients with sporadic Amyotrophic Lateral Sclerosis

ABSTRACT: DNA methylome, R-loop and clinical exome profiling of patients with sporadic Amyotrophic Lateral Sclerosis

PROVIDER: PRJNA1013548 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR25930831_1.fastq.gz	Fastqsanger.gz
	SRR25930831_2.fastq.gz	Fastqsanger.gz
	SRR25930832_1.fastq.gz	Fastqsanger.gz
	SRR25930832_2.fastq.gz	Fastqsanger.gz
	SRR25930833_1.fastq.gz	Fastqsanger.gz

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DNA methylome, R-loop and clinical exome profile of patients with sporadic Amyotrophic Lateral Sclerosis (RRBS)

Project description:DNA methylome, R-loop and clinical exome profile of patients with sporadic Amyotrophic Lateral Sclerosis (RRBS)

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DNA methylome, R-loop and clinical exome profile of patients with sporadic Amyotrophic Lateral Sclerosis (DRIP)

Project description:DNA methylome, R-loop and clinical exome profile of patients with sporadic Amyotrophic Lateral Sclerosis (DRIP)

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Project description:This experiment series sought to detect genome-wide methylation in sporadic amyotrophic lateral sclerosis brains and compare it to normal control brains. Methylation across the whole genome was measured in brain DNA of 10 SALS patients and 10 neurologically-normal controls. Methylated DNA was immunoprecipitated and interrogated by Affymetrix GeneChip Human Tiling 2.0R Array Sets. Methylation calls were compared between SALS patients and controls at each methylated site. Keywords: ChIP-Chip

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