Project description:Although accumulating evidence has shown that long non-coding RNAs (lncRNAs) are involved in multiple biological processes, considerably less is known regarding their functions in influenza A virus (IAV) replication. Here, lncRNA expression profiles were determined by RNA sequencing in three pairs of influenza virus A/Puerto Rico/8/34 (H1N1)-infected or uninfected A549 cells.
Project description:Untransfected (no siRNA), control siRNA or TOP1 siRNA treated A549 cells were infected with A/Puerto Rico/8/1934(ΔNS1) for 12 hours
Project description:The Virochip microarray (version 5.0, Viro5AGL-60K platform) was used to verify the presence or absence of Chikungunya virus in RNA extracts from asymptomatic blood donors located in Puerto Rico.
Project description:To further understand the molecular pathogenesis of the 2009 pandemic H1N1 influenza virus infection, we profiled cellular miRNAs of lung tissue from BALB/c mice infected with influenza virus BJ501 and a mouse-adapted influenza virus A/Puerto Rico/8/34 (H1N1)(PR8) as a comparison.
Project description:Untransfected (no siRNA), control siRNA or Xrn2 siRNA treated A549 cells were infected with A/Puerto Rico/8/1934(ΔNS1) for 4 hours 3 Biological Replicates per condition
Project description:Untransfected (no siRNA), control siRNA or SETX siRNA treated A549 cells were infected with A/Puerto Rico/8/1934(ΔNS1) for 4 hours 3 Biological Replicates per condition
Project description:Hispanic/Latino populations possess a complex genetic structure that reflects recent admixture among and potentially ancient substructure within Native American, European, and West African source populations. Here, we quantify genome-wide patterns of SNP and haplotype variation among 100 individuals with ancestry from Ecuador, Colombia, Puerto Rico, and the Dominican Republic genotyped using Illumina technology.
Project description:B6-CIITA-E cell line (C57Bl/6 fibroblasts expressing MHC-II molecules I-Ab and I-Ed) was infected with Influenza A virus (A/Puerto Rico/8/1934, PR8) or left uninfected (control), and the MHC-class II-associated peptidome analysed via immunopeptidomics.
