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Bulk RNA sequencing of total lung cells from 14 dpi of high-dose mtb on Atg14f/f and Atg14f/f-LysM-cre mice.

ABSTRACT: Bulk RNA sequencing of total lung cells from 14 dpi of high-dose mtb on Atg14f/f and Atg14f/f-LysM-cre mice.

PROVIDER: PRJNA1027360 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR26369649_1.fastq.gz	Fastqsanger.gz
	SRR26369649_2.fastq.gz	Fastqsanger.gz
	SRR26369650_1.fastq.gz	Fastqsanger.gz
	SRR26369650_2.fastq.gz	Fastqsanger.gz
	SRR26369651_1.fastq.gz	Fastqsanger.gz

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Bulk RNA sequencing of total lung cells from 14 dpi of high-dose mtb on Atg14f/f and Atg14f/f-LysM-cre mice.

Project description:We found that several autophagy genes in myeloid cells are required to protect against high-dose Mtb (~1000cfu) infection. To understand the immune cell population in these mice after high-dose Mtb infection and what may contribute to the susceptibility, we did bulk RNAseq on mice infected with high-dose of Mtb strain Erdman.

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