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Transcriptome-wide analysis of hidradenitis suppurativa

ABSTRACT: Transcriptome-wide analysis of hidradenitis suppurativa

PROVIDER: PRJNA1028532 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR26395301.fastq.gz	Fastqsanger.gz
	SRR26395302.fastq.gz	Fastqsanger.gz
	SRR26395303.fastq.gz	Fastqsanger.gz
	SRR26395304.fastq.gz	Fastqsanger.gz
	SRR26395305.fastq.gz	Fastqsanger.gz

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Transcriptome-wide analysis of hidradenitis suppurativa

Project description:The aim of this study was to obtain a better understanding of the molecular background of hidradenitis suppurativa (HS). Global transcriptome analysis of lesional and perilesional skin identifies numerous differentially expressed genes that display unique expression pattern in HS. Genes, whose expression is dysregulated in the skin of patients suffering from HS are novel biomarker candidates and potential therapeutic targets for HS.

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Project description:Molecular taxonomy and key signaling pathways of apocrine glands of patients with hidradenitis suppurativa were studied by whole transcriptome profiling. Dysregulated genes were detected by comparing lesional and non lesional skin obtained from male and female HS patients using the Agilent array platform.

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