Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of liver tissue extracted from mouse hepatectomy models (Control group vs. gelADSC group)

ABSTRACT: RNA-seq of liver tissue extracted from mouse hepatectomy models (Control group vs. gelADSC group)

PROVIDER: PRJNA1035069 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR26641888_1.fastq.gz	Fastqsanger.gz
	SRR26641888_2.fastq.gz	Fastqsanger.gz
	SRR26641889_1.fastq.gz	Fastqsanger.gz
	SRR26641889_2.fastq.gz	Fastqsanger.gz
	SRR26641890_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

RNA-seq of liver tissue extracted from mouse hepatectomy models (Control group vs. gelADSC group)

Project description:To clarify the difference in the RNA expression between the control group (hepatectomized mice treated with fibrin gel only) and the gelADSC group (hepatectomized mice treated with ADSC embedded in fibrin gel), we extracted RNAs from the liver tissue.

2023-11-05 | GSE246897 | GEO

Hepatectomy sham surgery 1h

Project description:4 Adult male Sprague-Dawley rats (275-350 g) were anesthetized and subjected to hepatectomy sham surgery (abdominal cavity was opened, liver was handled, but no tissue resection was made). 1 hour after the surgery rats were killed and liver samples were harvested. This study was conducted to analyzes the effects of surgical stress on gene expression levels in rat liver. It provides additional data to 1-6 h partial hepatectomy study (Series GSE7415). Keywords: 1h hepatectomy sham surgery

2007-09-26 | GSE9137 | GEO

Murine liver tissues: WT and Wip1 KO mice after Partial Hepatectomy at 24h and 36 h.

Project description:Transcriptional profiling of mouse liver tissues comparing Wild type liver tissues with Wip1 KO mice liver tissues after Partial Hepatectomy at 24h and 36 h. WT vs. Wip1 KO tissues after Partial Hepatectomy at 24h and 36 h .

2014-07-03 | E-GEOD-59023 | biostudies-arrayexpress

Hepatectomy sham surgery 1h

Project description:Hepatectomy sham surgery 1h

| PRJNA102679 | ENA

Human placental tissues:control group vs non-diabetic fetal macrosomia (NDFMS) group

Project description:Human placental tissues:control group vs non-diabetic fetal macrosomia (NDFMS) group

| PRJNA818658 | ENA

Comparison of hepatic gene change after partial hepatectomy

Project description:Partial hepatectomy, resection of a portion of liver mass, indues significant liver regenerative responses that consist of numerous genetic changes. To identify specific genetic changes, we compare the liver of mice underwent either hepatectomy or sham operation.

2010-11-01 | GSE22879 | GEO

mRNA profile between 1/3 partial hepatectomy (PH) and 2/3 PH at 24 hours

Project description:Six rats underwent partial hepatectomy (PH) (3, 1/3PH; 3, 2/3PH). The total mRNA of three rats each group were pooled and compared by microarray to selected the mRNA which differs between between 2/3PH with robust DNA replication and 1/3PH with a minimal replicative response.

2016-04-08 | GSE80030 | GEO

Expression data from rat hepatocyte during liver regeneration after partial hepatectomy

Project description:The recovery of liver mass is mainly mediated by proliferation and enlargement of hepatocytes after partial hepatectomy. Studying the gene expression profiles of hepatocytes after partial hepatectomy will be helpful in exploring the mechanism of liver regeneration. We used microarrays to further highlight the regulatory role of hepatocyte in liver regeneration at gene transcription level. Rat liver regeneration after partial hepatectomy (PH) is a good model to study the regulation of cell proliferation. We isolated hepatocytes from regenerating liver at 9 time points (2, 6, 12,24, 30, 36, 72, 120, and 168h) after PH and measured gene expression profiles of hepatocytes from 2h to 168h with rat Genome 230 2.0 gene chip. Each sample corresponding to one time point was hybridized onto one array. The experiment was repeated 3 times for each time point. In total, 10 time points were measured and 0h was used control group. After careful quality control analyses of each chip, Affymetrix GCOS 2.0 software was used to analyze the data. The relevance of gene expression profiles and biological processes was analyzed by bioinformatics and systems biology.

2014-02-28 | E-GEOD-55434 | biostudies-arrayexpress

Gene expression in the liver remnant is significantly affected by the size of partial hepatectomy - an experimental rat study

Project description:Background: Extended hepatectomies may result in post-hepatectomy liver failure, a condition with a high mortality. The main purpose of the present study was to investigate and compare the gene expression profiles in rats subjected to increasing size of partial hepatectomy. Methods: 40 Wistar rats were subjected to 30%, 70%, or 90% partial hepatectomy, sham operation or no operation. 24 hours following resection, liver tissue was harvested and genome-wide expression analysis was performed. Results: Cluster analysis revealed 2 main groupings, one containing the PH(90%) and one containing the remaining groups (baseline, sham, PH(30%) and PH(70%)). Categorization of specific affected molecular pathways in the PH(90%) group revealed a downregulation of cellular homeostatic functions degradation and biosynthesis, whereas proliferation, cell growth, and cellular stress and injury were upregulated in the PH(90%) group. After PH(90%), the main upregulated pathways were mTOR and ILK. The main activated upstream regulators were hepatocyte growth factor and transforming growth factor. Conclusion: With decreasing size of the future liver remnant, the liver tended to prioritize expression of genes involved in cell proliferation and differentiation at the expense of genes involved in metabolism and body homeostasis. This prioritizing may be an essential molecular explanation for post-hepatectomy liver failure.

2018-03-31 | GSE97429 | GEO

Whole genome profiling of liver sinusoidal endothelial cells (LSEC) before and after hepatectomy

Project description:compare acute gene expression changes in LSEC after hepatecomy WT C57BL/6N mice were either sham operated or underwent 2/3 hepatectomy. One day after operation, LSEC were isolated. RNA were immediatedly extracted for gene array.

2013-08-26 | E-GEOD-50046 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data