Mus musculus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA103617 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Gene expression comparison in between mitoNEET transgenic vs wild type subcutaneous adipose tissue
| PRJNA170378 | ENA
Project description:Expression data from AR3 transgenic and wild-type mouse prostates
| PRJNA226669 | ENA
Project description:The aim of the study was to investigate whether the trefoil peptide genes, in concerted action with a miRNA regulatory network, were contributing to nutritional maintrenance. Using a Tff2 knock-out mouse model, 48 specific miRNAs were noted to be significantly deregulated when compared to the wild type strain.
2012-01-01 | GSE25815 | GEO
Project description:The aim of the study was to investigate whether the trefoil peptide genes, in concerted action with a miRNA regulatory network, were contributing to nutritional maintrenance. Using a Tff3 knock-out mouse model, 21 specific miRNAs were noted to be significantly deregulated when compared to the wild type strain.
2010-09-20 | GSE23819 | GEO
Project description:Comparison of apoptosis related gene expression in p7-p14 mouse lenses
| PRJNA101989 | ENA
Project description:Lenses expression profile of DBL oncogene transgenic mice
| PRJNA116643 | ENA
Project description:comparison of Tdg wild type and knockout mouse embryo fibroblast lines
2011-03-07 | E-MEXP-2610 | biostudies-arrayexpress
Project description:Comparison of gene expression between wild-type and SERT knockout ileal mucosa
| PRJNA371612 | ENA
Project description:Comparison of gene expression between Ftx KO eyes and wild type eyes
| PRJNA392685 | ENA
Project description:Differential expression of HSF4 in null newborn mouse and wildtype lenses was examined to identify putative downstream targets of HSF4. To examine roles of Brg1 in mouse lens development, a dnBrg1 transgenic construct was expressed using the lens-specific aA-crystallin promoter in postmitotic lens fiber cells. Morphological studies revealed abnormal lens fiber cell differentiation in transgenic lenses resulting in cataract. Electron microscopic studies showed abnormal lens suture formation and incomplete karyolysis (denucleation) of lens fiber cells. To identify genes regulated by Brg1, RNA expression profiling was performed in E15.5 embryonic wild type and dnBrg1 transgenic lenses. In addition, comparisons between differentially expressed genes in dnBrg1 transgenic, Pax6 heterozygous, and Hsf4 homozygous lenses identified multiple genes co-regulated by Brg1, Hsf4 and Pax6. Among them DNase IIb, a key enzyme required for lens fiber cell denucleation, was found downregulated in each of the Pax6, Brg1 and Hsf4 model systems. Lens-specific deletion of Brg1 using conditional gene targeting demonstrated that Brg1 was required for lens fiber cell differentiation and indirectly for retinal development but was not essential for lens lineage formation. Keywords: Differential mRNA Expression Three biological replicate experiments were performed with HSF null and wildtype lenses.
2010-12-01 | E-GEOD-22362 | biostudies-arrayexpress