Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: RNA sequencing of Drosophila accessory gland tissue

PROVIDER: PRJNA1040452 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR26832200_1.fastq.gz	Fastqsanger.gz
	SRR26832200_2.fastq.gz	Fastqsanger.gz
	SRR26832201_1.fastq.gz	Fastqsanger.gz
	SRR26832201_2.fastq.gz	Fastqsanger.gz
	SRR26832202_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 68

Similar Datasets

Project description:ATAC seq of Drosophila accessory gland tissue

| PRJNA993436 | ENA

Regulation of male fertility and accessory gland gene expression by the Drosophila DHR39 nuclear receptor

Project description:Here we show that the Drosophila nuclear receptor DHR39 is necessary for male reproduction and acts as a global regulator of accessory gland gene expression. Mutants for the DHR39 transcription factor are sterile, with the majority of accessory gland genes expressed at reduced levels. Specific depletion of DHR39 within the accessory gland is sufficient to reduce male fecundity and accessory gland gene expression. Restoration of DHR39 in the accessory gland of DHR39 mutants rescues this sterility and transcriptional reduction. We conclude that DHR39 is a key regulator of most accessory gland genes, including ovulin and sex peptide, and is necessary for male fertility.

2021-01-01 | GSE159502 | GEO

Oncogenic signaling in the adult Drosophila prostate-like accessory gland leads to activation of a conserved pro-tumorigenic program, in the absence of proliferation

Project description:The Drosophila melanogaster male accessory gland (AG) is crucial for reproductive success, producing seminal fluid proteins that impact female post-mating behavior and physiology. To understand the regulatory networks governing accessory gland function, we conducted a bulk RNA sequencing (RNA-Seq) study to analyze the effects of overexpressing three key regulatory genes: dMyc, Yorkie (Yki), and the E2F-Dp heterodimer, compared to wild-type (WT) controls. We found upregulated and downregulated genes in each condition compared to controls, affecting immune response, cell cycle, stress response, and reproductive functions. In both Yki constitutively active, E2F+Dp and dMyc, E2F+DP conditions, several genes known to be involved in wound healing and tumorigenic models in flies were upregulated, including JNK signaling targets Ets21C, MMP1, puckered, and Jak/STAT signaling pathway ligands upd2 and upd3. Conversely, accessory gland-specific genes, such as many Accessory Gland Proteins (Acps), and genes involved in fertility, mating behavior, and sperm competition were downregulated. There was a strong overlap between the Yki constitutively active, E2F+Dp and dMyc, E2F+Dp gene expression signatures, converging on genes commonly misregulated in proliferative tumor models in various larval tissues, including imaginal discs and brains. This study provides insights into the molecular mechanisms by which key regulatory genes influence the function and integrity of the Drosophila male accessory gland.

2024-10-01 | GSE270145 | GEO

Drosophila melanogaster and Drosophila simulans

Project description:Comparative accessory gland transcriptomics in Drosophila

| PRJNA913156 | ENA

Project description:Ovary, Testis and Accessory Gland sequencing of Drosophila species

| PRJNA764902 | ENA

Project description:RNA sequencing of squid's accessory nidamental gland

| PRJNA814067 | ENA

Project description:Single-nucleus transcriptomes of the Drosophila accessory gland

| PRJNA741528 | ENA

Compartmentalization and modulation of reproductive protein networks in response to experimental sexual selection

Project description:Here we directly test the hypothesis that PCSS results in rapid evolution of the entire male accessory gland proteome and protein networks by taking a system-level approach, combining divergent experimental evolution of PCSS in Drosophila pseudoobscura (Dpse), high resolution mass spectrometry (MS) and proteomic discovery, bioinformatics and population genetic analyses.

2019-02-18 | PXD012545 | Pride

Project description:Population transcriptomes of the accessory gland and testis in Drosophila melanogaster

| PRJNA890704 | ENA

Sepsis punctum

Project description:Sepsis punctum Accessory Gland Transcriptome

| PRJNA765219 | ENA