Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

M6A related mRNAs in ovarian-endometriosis control vs normal endometrial tissue

ABSTRACT: m6A related mRNAs in ovarian-endometriosis control vs normal endometrial tissue

PROVIDER: PRJNA1044821 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Project description:aberrant m6A- related mRNAs in EI and NE tissues were uncovered

2024-11-22 | GSE248593 | GEO

Endometrial methylome of patients without endometriosis

Project description:Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes and the menstrual cycle phase-dependent epigenetic signature should be considered when studying endometrial disorders. So far, no studies have been performed to evaluate the menstrual cycle influences and endometriosis-specific endometrial methylation pattern at the same time. Therefore, we used Infinium HumanMethylation 450K BeadChip arrays to explore DNA methylation profiles of endometrial tissues from various menstrual cycle phases. Infinium HumanMethylation 450K BeadChip arrays were used to explore DNA methylation profiles of endometrial tissues from mid secretory cycle phase from 17 patients without endometriosis

2016-02-15 | E-GEOD-73949 | biostudies-arrayexpress

Endometrial methylome of patients with endometriosis

Project description:Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes and the menstrual cycle phase-dependent epigenetic signature should be considered when studying endometrial disorders. So far, no studies have been performed to evaluate the menstrual cycle influences and endometriosis-specific endometrial methylation pattern at the same time. Therefore, we used Infinium HumanMethylation 450K BeadChip arrays to explore DNA methylation profiles of endometrial tissues from various menstrual cycle phases. Infinium HumanMethylation 450K BeadChip arrays were used to explore DNA methylation profiles of endometrial tissues from various menstrual cycle phases from 24 patients with endometriosis

2016-02-15 | E-GEOD-73948 | biostudies-arrayexpress

Proteomics of ectopic endometrial cell-derived exosomes in endometriosis

Project description:We primary cultured ectopic endometrial cells from patients with endometriosis (2 cases) and without endometriosis(2 cases) and collected cell culture supernatants（P0). We isolated exosomes from cell culture supernatants by differential centrifugation and then performed proteome analysis on the two groups of exosomes to investigate the role of ectopic endometrial cell-derived exosomes in the development of endometriosis.

2022-06-09 | PXD033124 | Pride

Endometrial methylome of patients without endometriosis

2016-02-15 | GSE73949 | GEO

Endometrial methylome of patients with endometriosis

2016-02-15 | GSE73948 | GEO

Global m6A-modified mRNAs in undecidualized and decidualized primary human endometrial stromal cells [meRIP-seq]

Project description:Global m6A-modified mRNAs in undecidualized and decidualized primary human endometrial stromal cells were analyzed by using methylated RNA immunoprecipitation sequencing (MeRIP-seq)

2024-04-14 | GSE263331 | GEO

Endometriosis induced menstrual cycle dependent and independent endometrial transcriptomic dysregulation

Project description:We collected the eutopic endometrial biopsy from control women and women with endometriosis at both proliferative and secretory for RNA-seq analysis. We found regardless of endometriosis or not, the menstrual stage differences proliferative vs secretory accounts for the most changes of the transcriptome of all endometrial biopsy samples. Distinct and conserved gene expression patterns were induced by endometriosis at proliferative and secretory phases. From proliferative to secretory phase, endometriosis not only ablated the gene expression changes of some menstrual cycle dependent genes but also stimulated the menstrual cycle dependent expression changes in some new genes suggesting a dyssynchronous endometrium. Furthermore, we found eight endometriosis altered DEGs in our datasets are proximally localized to the endometriosis associated SNP at both proliferative and secretory phases. More interestingly, 75 published endometrial receptivity related genes were altered by endometriosis at secretory phase.

2024-12-31 | GSE272606 | GEO

Discovery study in endometrial samples using RNA-HighSeq to build classifiers to differentiate between control patients and adenomyosis, ovarian endometriosis and deep infiltrating endometriosis

Project description:A discovery study using RNA-HighSeq from 37 endometrial biopsies was performed to build classifiers that differentiate between control patients and adenomyosis, ovarian endometriosis and deep infiltrating endometriosis. Total RNA was extracted from endometrial biopsies. We found an AUC of 0.97 where the classifier differentiated almost perfectly all three diseases together from the control group when including 11 phenotypic variables of the patients in the classifier.

2024-01-31 | GSE193928 | GEO

Single-cell Transcriptomics of Endometrial Cells from Patients with Minimal/mild Endometriosis.

Project description:We profiled the transcriptomes of 128, 243 endometrial cells from 6 infertile minimal/mild endometriosis patients and 4 controls. Our results provide new insight of pathogenesis and impaired endometrial receptivity of endometriosis.

2023-03-28 | GSE214411 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data