Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Schizosaccharomyces pombe

ABSTRACT: Tup11D,12D/WT

OTHER RELATED OMICS DATASETS IN: GSE4566

PROVIDER: PRJNA104677 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Schizosaccharomyces pombe

Project description:Ssn6HA-ts VS WT @ 36 Deg

| PRJNA104377 | ENA

The fission yeast Schizosaccharomyces pombe: H3K9me2 and Fep1-GFP ChIP-chip

Project description:ChIP-chip analyses of H3K9me2 (in WT 30°C, WT 18°C, ccr4∆ 18°C, ccr4∆fep1 18°C, ago1∆ 18°C, WT + 2,2′-bipyridyl 18°C), Fep1-GFP (in WT), Ssn6-MYC ChIP in WT and Fep1∆.

2018-05-08 | GSE104528 | GEO

Schizosaccharomyces pombe

Project description:Small RNA profiles in wt and swi6 deletion strains

| PRJNA290002 | ENA

Schizosaccharomyces pombe

Project description:Tiling ChIP-CHIP Ssn6-GFP, Tp11-GFP, Tup12-GFP Hst4 vs WT Expression

| PRJNA153235 | ENA

Schizosaccharomyces pombe

Project description:ChIP-chip of histone variants and modifications in S. pombe WT and various mutants

| PRJNA144847 | ENA

The fission yeast Schizosaccharomyces pombe: H3K9me2, Erh1-GFP and CFP-Mmi1 ChIP-chip

Project description:ChIP-chip analyses of H3K9me2 (in WT, erh1∆, mmi1∆ and ccr4∆), Erh1-GFP (in WT and mmi1∆) and CFP-Mmi1 (in WT)

2016-06-15 | GSE76111 | GEO

Schizosaccharomyces pombe

Project description:ChIP-chip analyses of H3K9 acetylation in WT, alp13 deletion and pst1-1 mutant S.pombe cells.

| PRJNA104037 | ENA

Schizosaccharomyces pombe

Project description:Expression profiling in alp13 deletion, clr6-1 mutant and pst1-1 mutant, versus WT S. pombe cells.

| PRJNA104069 | ENA

Characterisation of Schizosaccharomyces pombe α-actinin.

Project description:The actin cytoskeleton plays a fundamental role in eukaryotic cells. Its reorganization is regulated by a plethora of actin-modulating proteins, such as a-actinin. In higher organisms, α-actinin is characterized by the presence of three distinct structural domains: an N-terminal actin-binding domain and a C-terminal region with EF-hand motif separated by a central rod domain with four spectrin repeats. Sequence analysis has revealed that the central rod domain of α-actinin from the fission yeast Schizosaccharomyces pombe consists of only two spectrin repeats. To obtain a firmer understanding of the structure and function of this unconventional α-actinin, we have cloned and characterized each structural domain. Our results show that this a-actinin isoform is capable of forming dimers and that the rod domain is required for this. However, its actin-binding and cross-linking activity appears less efficient compared to conventional α-actinins. The solved crystal structure of the actin-binding domain indicates that the closed state is stabilised by hydrogen bonds and a salt bridge not present in other α-actinins, which may reduce the affinity for actin.

| S-EPMC4824898 | biostudies-literature

Nedd8 processing enzymes in Schizosaccharomyces pombe.

Project description:BackgroundConjugation of the ubiquitin-like modifier Nedd8 to cullins is critical for the function of SCF-type ubiquitin ligases and thus facilitates ubiquitin conjugation and ultimately degradation of SCF substrates, including several cell cycle regulators. Like ubiquitin, Nedd8 is produced as a precursor that must first be processed before it becomes active. In Saccharomyces cerevisiae this is carried out exclusively by the enzyme Yuh1.ResultsHere we show that in the fission yeast, Schizosaccharomyces pombe, the Yuh1 orthologue, Uch1, is not the sole Nedd8 processing enzyme. Instead it appears that deubiquitylating enzymes can efficiently process the Nedd8 precursor in vivo.ConclusionsSeveral enzymes contribute to Nedd8 precursor processing including a number of deubiquitylating enzymes.

| S-EPMC3602023 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data