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Effect of PTEN treatment on the subcutaneous tumor formation model of PTEN knockout B16F10 cells in C57BL/6J mice

ABSTRACT: Effect of PTEN treatment on the subcutaneous tumor formation model of PTEN knockout B16F10 cells in C57BL/6J mice

PROVIDER: PRJNA1047093 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR27008583_1.fastq.gz	Fastqsanger.gz
	SRR27008583_2.fastq.gz	Fastqsanger.gz
	SRR27008584_1.fastq.gz	Fastqsanger.gz
	SRR27008584_2.fastq.gz	Fastqsanger.gz

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Effect of PTEN treatment on the subcutaneous tumor formation model of PTEN knockout B16F10 cells in C57BL/6J mice

Project description:PTEN treatment can affect the tumor growth of PTEN knockout B16-F10 cells in C57BL/6J mice，We hope to analyze the changes that occur in various cells in tumors through single-cell RNA sequencing.

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Transcriptomics of PTEN knockout B16-F10 cells in C57BL/6J mice model treated with PTEN

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Project description:extracellular PTEN treatment did not affect the growth of PTEN knockout B16-F10 cells cultured in vitro. , To investigate whether extracellular PTEN act on the tumor microenvironment to exert a tumor-suppressive role in vivo，molecular changes caused by PTEN treatment inside the B16-F10-PTEN tumors were monitored by RNA sequencing.

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