Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of methionine-chorine-deficient diet (MCD) on microRNA expression in murine liver [miRNA]

ABSTRACT: Effect of methionine-chorine-deficient diet (MCD) on microRNA expression in murine liver [miRNA]

PROVIDER: PRJNA1049370 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Effect of methionine-chorine-deficient diet (MCD) in murine liver

Project description:Effect of methionine-chorine-deficient diet (MCD) in murine liver

| PRJNA1049364 | ENA

Effect of methionine-chorine-deficient diet (MCD) on microRNA expression in murine liver [miRNA]

Project description:It is known that administration of MCD induces a severe state of hepatic fibrosis in mice. Recently, many microRNAs (miRNAs) with pro- or anti-fibrotic properties have been identified during hepatic fibrosis. To attempt to elucidate molecular mechanism of hepatic fibrosis involved in miRNA fnction, we performed comprehensive analysis of miRNA expression by microarray using RNAs prepared from liver of wild-type mice fed with normal diet (ND) or MCD.

2023-12-06 | GSE249486 | GEO

Effect of methionine-chorine-deficient diet (MCD) on whole gene expression in murine liver [mRNA]

Project description:It is known that administration of MCD induces a severe state of hepatic fibrosis in mice. To attempt to elucidate molecular mechanism of hepatic fibrosis, we performed whole transcriptome analysis by microarray using RNAs prepared from liver of wild-type mice fed with normal diet (ND) or MCD.

2023-12-06 | GSE249485 | GEO

Effect of methionine-chorine-deficient diet (MCD) on whole gene expression in murine liver [mRNA]

Project description:Effect of methionine-chorine-deficient diet (MCD) on whole gene expression in murine liver [mRNA]

| PRJNA1049371 | ENA

Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for the histone modifications H3K27ac and H3K9me3 in liver tissues from MCD and regular chow diet mice

Project description:Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for the histone modifications H3K27ac and H3K9me3 in liver tissues from Methionine- and choline-deficient diet (MCD) and regular chow diet mice.

2024-05-02 | GSE266077 | GEO

Effect of methionine-chorine-deficient diet (MCD) in murine liver

Project description:This SuperSeries is composed of the SubSeries listed below.

2023-12-06 | GSE249487 | GEO

Difference of microRNA expressions between a mouse model of NASH(MCD diet) and normal mouse.

Project description:The microRNAs expression was markedly altered with the MCD diet. Using a custom microarray platform, we analyzed the expression levels of 1135 mouse microRNA probes in liver tissue that were fed MCD diet.

2015-03-01 | E-GEOD-55593 | biostudies-arrayexpress

Effect of HGPP on MCD-diet NASH on gene expression during liver of C57BL/6 mice

Project description:Recent studies have revealed the pivotal role of gut microbiota in the precession of liver diseases including non-alcoholic steatohepatitis (NASH). Many natural herbs, such as Gynostemma pentaphyllum (GP), have been extensively used applied in the treatment prevention of NASH, while the bioactive components and underlying mechanism remain unclear. The aim of this study was to investigate whether the polysaccharides of GP (GPP) has the protective effect on of NASH and to explore the potential mechanism underlying these effects. To investigate the function high dose of GPP(HGPP) in the regulation of hepatic gene expression, C57BL/6 male mice were fed with methionine-choline-deficient (MCD) diet for 4 weeks to induce NASH, and administered daily oral gavage of the sodium carboxymethylcellulose (CMC-Na) for model group, HGPP for experimental group, compared with normal control methionine-choline-sufficient (MCS) group.

2022-06-16 | GSE205974 | GEO

Difference of microRNA expressions between a mouse model of NASH(MCD diet) and normal mouse.

Project description:The microRNAs expression was markedly altered with the MCD diet.

2015-03-01 | GSE55593 | GEO

Effects of dual agonist of GLP1 and GCGR on animal model of NAS (MCD diet) and hepatic regeneration

Project description:The genomic analysis of liver from mice fed with standard or methyl and choline deficient (MCD) diet and treated with dual agonist of GLP1R/GCGR during two weeks before 70% partial hepatectomy (PH) and after 2 weeks PH resulted in a set of genes regulated by diet and other set regulated differentially by treatment in MCD treated animals. These genes are apparently responsible for the reversion and prevention of NAS and improvement in hepatic regeneration induced by drug treatment All microarray analyses were performed with RNA samples obtained from four independent liver from animals with different diet and drug treatmens.

2016-02-23 | E-GEOD-78170 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data