Ontology highlight
ABSTRACT:
PROVIDER: PRJNA1049640 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Listeria monocytogenes in rabbit meat processing plant
| PRJNA396103 | ENA
Project description:In order to further improve the meat quality performance of Shuxing No. 1 rabbit, IRA rabbits with better meat quality performance were selected for comparative study. The proteomic data of longissimus dorsi muscle of two breeds of rabbits were obtained.
2023-11-22 | PXD047148 |
Project description:<p>This study aims to investigate the potential regulatory network responsible for the meat quality using multi-omics to help developing better varieties. Slaughter performance and meat quality of Shuxing No.1 rabbit outperformed Yila rabbit. Differentially expressed genes (DEGs) and differentially abundance proteins (DAPs) were involved in meat quality-related pathways, such as PI3K-Akt and MAPK signaling pathway. Only SMTNL1 and PM20D2 shared between DEGs and DAPs. Olfactory-sensitive undecanal, a differentially abundant metabolite (DAM) in volatilomics (vDAMs), correlated with all of the remaining 11 vDAMs and most of 12 vDAMs were associated with amino acid metabolism. Integration revealed that 829 DEGs/DAPs were associated with 15 DAMs in four KEGG pathways, such as melatonin (a DAM in widely targeted metabolomics) was significantly positively correlated with ALDH and negatively correlated with RAB3D and CAT in tryptophan metabolism pathway. This study sheds light on the potential mechanisms that contribute to the improved meat quality and flavor.</p><p><br></p><p><strong>SPME-GC-MS assay</strong> is reported in the current study <a href='https://www.ebi.ac.uk/metabolights/MTBLS8958' rel='noopener noreferrer' target='_blank'><strong>MTBLS8958</strong></a>.</p><p><strong>UPLC-MS/MS assays</strong> are reported in <a href='https://www.ebi.ac.uk/metabolights/MTBLS8957' rel='noopener noreferrer' target='_blank'><strong>MTBLS8957</strong></a>.</p>
2024-01-18 | MTBLS8958 | MetaboLights
Project description:<p>This study aims to investigate the potential regulatory network responsible for the meat quality using multi-omics to help developing better varieties. Slaughter performance and meat quality of Shuxing No.1 rabbit outperformed Yila rabbit. Differentially expressed genes (DEGs) and differentially abundance proteins (DAPs) were involved in meat quality-related pathways, such as PI3K−Akt and MAPK signaling pathway. Only SMTNL1 and PM20D2 shared between DEGs and DAPs. Olfactory-sensitive undecanal, a differentially abundant metabolite (DAM) in volatilomics (vDAMs), correlated with all of the remaining 11 vDAMs, and most of 12 vDAMs were associated with amino acid metabolism. Integration revealed that 829 DEGs/DAPs were associated with 15 DAMs in four KEGG pathways, such as melatonin (a DAM in widely targeted metabolomics) was significantly positively correlated with ALDH and negatively correlated with RAB3D and CAT in tryptophan metabolism pathway. This study sheds light on the potential mechanisms that contribute to the improved meat quality and flavor.</p><p><br></p><p><strong>UPLC-MS/MS assays</strong> are reported in the current study <a href='https://www.ebi.ac.uk/metabolights/MTBLS8957' rel='noopener noreferrer' target='_blank'><strong>MTBLS8957</strong></a>.</p><p><strong>SPME-GC-MS assay</strong> is reported in <a href='https://www.ebi.ac.uk/metabolights/MTBLS8958' rel='noopener noreferrer' target='_blank'><strong>MTBLS8958</strong></a>.</p>
2024-01-18 | MTBLS8957 | MetaboLights
Project description:Despite the growing interest in the rabbit model for developmental and stem cell biology, the characterization of embryos at the molecular level is still poorly documented. We conducted a transcriptome analysis of rabbit pre-implantation embryos from E2.7 (morula stage) to E6.6 (early primitive streak stage) using SmartSeq2 bulk RNA-sequencing, single-cell 10X Genomics RNA-seq and single-cell Biomark qPCR. In parallel, we studied oxidative phosphorylation and glycolysis and analyzed active and repressive epigenetic modifications during blastocyst formation and expansion. We generated a transcriptomic, epigenetic, and metabolic map of the pluripotency continuum in rabbit preimplantation embryos and identified novel markers of naïve pluripotency that might be instrumental for deriving naïve pluripotent stem cell lines. Although the rabbit is evolutionarily closer to mice than to primates, we found that the transcriptome of rabbit epiblast cells shares common features with that of humans and non-human primates.
2022-08-22 | GSE180048 | GEO
Project description:The virulence of Mycobacterium tuberculosis (Mtb), either as mostly aggregates or single cells (Mtb-SC), was compared using a rabbit model of pulmonary infection. Our hypothesis is that aggregation contributes to enhanced virulence of Mtb. Rabbit lung transcriptome was analyzed by RNAseq to identify differentially regulated gene networks and pathways between Mtb-AG and Mtb-SC infection of rabbit lungs soon after seeding of the bacteria (24 hours post-inoculation).
2021-09-22 | GSE176139 | GEO
Project description:To identify transcriptional markers for beef traits related to meat tenderness and moisture, we measured the transcriptome of the Longissimus dorsi skeletal muscle in 10 Korean native cattle (KNC). We analyzed the correlation between the beef transcriptome and measurements of four different beef traits, shear force (SF), water holding capacity (WHC), cooking loss (CL), and loin eye area (LEA). We obtained non-overlapping and unique panels of genes showing strong correlations (|r| > 0.8) with SF, WHC, CL, and LEA, respectively. Functional studies of these genes indicated that SF was mainly related to energy metabolism, and LEA to rRNA processing. Interestingly, our data suggested that WHC is influenced by protein metabolism. Overall, the skeletal muscle transcriptome pointed to the importance of energy and protein metabolism in determining meat quality after the aging process. The panels of transcripts for beef traits may be useful for predicting meat tenderness and moisture. Experiment Overall Design: Gene expression profiles were correlated with beef traits measured at the same cattle.
2008-11-01 | E-GEOD-9256 | biostudies-arrayexpress
Project description:Genome-wide H3S10ph marks from mouse gastrocnemius muscles after 50 eccentric contractions compared to contralateral unstimulated gastrocnemius muscles from the same mice.
2020-05-17 | GSE139661 | GEO