Project description:We performed next generation sequencing between control CRC cells and CRC cells with GPT1 overexpression to identify GPT1 regulating signaling pathway
Project description:We performed next generation sequencing between control CRC cells and CRC cells with PNISR knockdown to identify PNISR regulating alternative splicing
Project description:We performed Next Generation Sequencing of normal human intestinal epithelial cell lines, CRC cell lines and CRC cell lines with hypoxia treatment to identify the differentially expressed non-coding RNAs.
Project description:Colorectal cancer (CRC) is the third leading cause of cancer mortality worldwide. However, the underlying mechnism of cancer development remain largely unknown. The aim of this study is to analyze transcriptome expression profile to understand the molecular mechanism in CRC development.
Project description:Next Generation Sequencing of normal human intestinal epithelial cell lines, CRC cell lines and CRC cell lines with hypoxia treatment
Project description:The study was conducted as the marker discovery phase to identify potential microRNA (miRNA) candidates for colorectal cancer (CRC) screening. Genome-wide profiling with next-generation sequencing (NGS) was performed using plasma samples from 20 newly diagnosed CRC cases and 20 controls free of colorectal neoplasms matched by age and sex.