Project description:Origanum L. (Lamiaceae) is an important genus of medicinal and aromatic plants used in the traditional medicine since ancient times as culinary herbs and remedies. The effects of Origanum majorana-based aromatherapy was investigated in an Alzheimer's amyloid beta1-42 rat model. Protein extracts from brain tissue containing hippocampi were analyzed by label-free quantitative LC-HDMSE. Proteins whose expression seemed influenced by Origanum majorana-based aromatherapy were assigned as representatives of biological processes, which were further targeted using well established biochemical/molecular assays.
