Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of knocking out RNVU1-18 on gene expression

ABSTRACT: Effect of knocking out RNVU1-18 on gene expression

PROVIDER: PRJNA1064172 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR27532967_1.fastq.gz	Fastqsanger.gz
	SRR27532967_2.fastq.gz	Fastqsanger.gz
	SRR27532968_1.fastq.gz	Fastqsanger.gz
	SRR27532968_2.fastq.gz	Fastqsanger.gz
	SRR27532969_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Effect of knocking out RNVU1-18 on gene expression

Project description:Test transcripts in WT and RNVU1-18-/- A549 cells

2024-01-17 | GSE253189 | GEO

Effect of knocking out SOCS3 in mouse ES cells

Project description:Series contains four arrays - two wildtype, two null. The experiment studied the effect of knocking out SOCS3 in mouse ES cells. Keywords: other

2005-02-02 | GSE2202 | GEO

Transcription profiling of mouse embryos at 8.5 and 12 days to study the effect of knocking out RUNX1 (a.k.a. AML1) gene

Project description:Series of samples studying effect of knocking out RUNX1 (a.k.a. AML1) in mouse embryos at 8.5 and 12 days. Wildtype and knockout animals at the two time points were generated and all conditions done in duplicate.

2007-08-09 | E-GEOD-2592 | biostudies-arrayexpress

Transcriptome measurements after knocking out the UMLILO lncRNA

Project description:Transcriptome measurements after knocking out the UMLILO lncRNA

| PRJNA493788 | ENA

Transcriptome measurements after knocking out the UMLILO lncRNA

Project description:Purpose: Assess whether knocking out the UMLILO lncRNA altered the expression of genes transcribed within the CXCL chemokine TAD Outcome: To confirm whether the effect of UMLILO was limited to the CXCL TAD. Adeno-associated viral vectors (AAVs) were constructed that contain CRISPR/Cas9 and guides targeting UMLILO to delete the full length UMLILO transcript. RNAseq was performed on a transduced THP-1 population to verify genome-wide effects of UMLILO depletion. This revealed that IL8, CXCL1, 2, 3 transcription was abrogated, but a similar effect was not seen for genes located outside of the CXCL TAD boundary

2018-10-15 | GSE120621 | GEO

Transcriptional changes induced by ADH5 knocking out in HeLa cells.

Project description:Transcriptional changes induced by ADH5 knocking out in HeLa cells.

| PRJNA868944 | ENA

Knocking out BATF improves CAR-T cell efficacy by resisting exhaustion and forming central memory cells

Project description:Chimeric antigen receptor modified T (CAR-T) cell therapy has limited efficacy against solid tumor, one major challenge is T cell exhaustion. To address this challenge, we performed a candidate gene screen using a hypofunction CAR-T cell model, and found that knocking out BATF improved the performance of CAR-T cells. In different types of CAR-T cells and mouse OT-1 cells, knocking out BATF endows T cells with improved resistance to exhaustion and better tumor eradication efficacy. We find that BATF binds to and up-regulates a subset of exhaustion genes in human CAR-T cells. Furthermore, BATF regulates the expression of genes involved in the development of effector and memory cells, and knocking out BATF shifts the population towards more central memory subset. Therefore, we conclude that BATF is a key factor limiting CAR-T cell function, and its depletion improves CAR-T cells efficacy against solid tumor.

2022-10-12 | GSE215086 | GEO

microRNA expression changes after knocking out MYEOV in two human pancreatic cancer cell lines

Project description:microRNA expression changes after knocking out MYEOV in two human pancreatic cancer cell lines

| PRJNA601780 | ENA

Impact of knocking out Ppargc1a in intestinal stem cells on mucosal homeostasis

Project description:Impact of knocking out Ppargc1a in intestinal stem cells on mucosal homeostasis

| PRJNA778403 | ENA

Effect of knocking down HOXB9 in gastric cancer cells

Project description:Effect of knocking down HOXB9 in gastric cancer cells

| PRJNA928345 | ENA