Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

NOVA1-CLIP in cortex, midbrain and cerebellum of NOVA1hu/hu mice and NOVA1wt/wt mice [CLIP-Seq]

ABSTRACT: NOVA1-CLIP in cortex, midbrain and cerebellum of NOVA1hu/hu mice and NOVA1wt/wt mice [CLIP-Seq]

PROVIDER: PRJNA1064991 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR29293580.fastq.gz	Fastqsanger.gz
	SRR29293581.fastq.gz	Fastqsanger.gz
	SRR29293582.fastq.gz	Fastqsanger.gz
	SRR29293583.fastq.gz	Fastqsanger.gz
	SRR29293584.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 18

Similar Datasets

NOVA1-CLIP in cortex, midbrain and cerebellum of NOVA1hu/hu mice and NOVA1wt/wt mice [CLIP-Seq]

Project description:Dissected brain regions (cortex, midbrain and cerebellum) from P21 NOVA1hu/hu mice and NOVA1wt/wt mice were subjected to CLIP to detect NOVA1 binding positions on transcripts

2024-12-11 | GSE253296 | GEO

NOVA1 HITS-CLIP in wild-type mouse diencephalon/ mesencephalon (P21)

Project description:Mouse diencephalon/ mesencephalon samples from P21 wild-type were subjected to HITS-CLIP to detect NOVA1 binding positions on RNA

2024-08-15 | GSE212547 | GEO

NOVA2 and NOVA1 HITS-CLIP in wild-type mouse cortex (E18.5)

Project description:Mouse cortex samples from E18.5 wild-type were subjected to HITS-CLIP to detect NOVA2 and NOVA1 binding positions on RNA

2016-05-26 | GSE69710 | GEO

NOVA1 HITS-CLIP in wild-type mouse diencephalon/ mesencephalon (P21)

Project description:NOVA1 HITS-CLIP in wild-type mouse diencephalon/ mesencephalon (P21)

| PRJNA875941 | ENA

CLIP (NOVA1 & AGO) and RNAseq (control & NOVA1KD) in human GBM cells

Project description:CLIP (NOVA1 & AGO) and RNAseq (control & NOVA1KD) in human GBM cells

| PRJNA1011395 | ENA

Effects of Nova1 Deletion on Gene Expression in Tissues and Cells

Project description:To elucidate the function of Nova1 in neurons, especially in inhibitory neurons, gene expression profiling analysis (RNAseq, TRAP-seq) was performed using Nova1 conditional knockout mice and their primary neurons.

2024-08-15 | GSE212473 | GEO

Effects of Nova1 I197V substitution on Gene Expression in Brain Tissues [RNA-Seq]

Project description:To elucidate the effect of human specific one amino acid substitution of Nova1 (I197V) in mice, gene expression profiling analysis was performed using humanized Nova1 mice (NOVA1hu/hu) and their littermate control mice (NOVA1wt/wt).

2024-12-11 | GSE253297 | GEO

CLIP (NOVA1 & AGO) and RNAseq (control & NOVA1KD) in human GBM cells

Project description:GBM cells derived from a patient were subjected to CLIP and RNAseq assays to for transcriptome analysis (CLIP and RNAseq).

2024-03-06 | GSE242124 | GEO

Nova1 is a master regulator of alternative splicing in pancreatic beta cells

Project description:Alternative splicing (AS) is a fundamental mechanism for the regulation of gene expression. It affects more than 90% of human genes but its role in the regulation of pancreatic beta cells, the producers of insulin, remains unknown. Our recently published data indicated that the M-bM-^@M-^\neuron specificM-bM-^@M-^] Nova1 splicing factor is expressed in pancreatic beta cells. We have presently coupled specific knockdown (KD) of Nova1 with RNA-sequencing to determine all splice variants and downstream pathways regulated by this protein in beta cells. Nova1 KD altered the splicing of nearly 5000 transcripts. Pathway analysis indicated that these genes are involved in exocytosis, apoptosis, insulin receptor signalling, splicing and transcription. In line with these findings, Nova1 silencing inhibited insulin secretion and induced apoptosis basally and after cytokine treatment in rodent and human beta cells. These observations identify a novel layer of regulation of beta cell function, namely AS controlled by key splicing regulators such as Nova1. 3 batch of primary rat pancreatic beta cells were examined under 2 conditions: control and with Nova1 splicing factor knock-down

2014-10-01 | E-GEOD-59633 | biostudies-arrayexpress

RNAseq in E18.5 wild-type, Nova2-KO, and Nova1-KO mouse cortex and mid- and hind-brain

Project description:We sequenced mRNA from E18.5 mouse cortex (3 wild-type vs 3 Nova2-/- and 3 wild-type vs 3 Nova1-/-) and from E18.5 mouse mid- and hind-brain (3 wild-type vs 3 Nova1-/-) to compare gene expression level and alternative splicing events between wild-type and Nova mutant mice.

2016-05-26 | GSE69709 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data