Project description:Comparative analysis of genome wide binding profile of Ncb2 in azole sensitive (AS, Gu4) and azole resistant (AR, Gu5) clinical isolates of Candida albicans. The goal was to study the role of Ncb2 in acquisition of drug resistance by comparing the binding profiles of Ncb2 in both the isolates.
2017-08-01 | GSE76858 | GEO
Project description:Whole genome sequencing of Candida glabrata clinical bloodstream isolates
| PRJNA1069094 | ENA
Project description:Whole genome sequencing of Candida krusei clinical bloodstream isolates
| PRJNA1079378 | ENA
Project description:Whole genome sequencing of Candida dubliniensis clinical bloodstream isolates
| PRJNA1067644 | ENA
Project description:Whole genome sequencing of Candida parapsilosis clinical bloodstream isolates
Project description:RNA sequencing was performed on Candida albicans clinical isolates that display normal (isolates: 3560, 3605, 3609, 4108, 4259) or aberrant (isolates: 3534, 3544, 3621, 3636, 4036) beta-glucan masking in response to lactate and hypoxia. Each clinical isolate was grown to exponential phase in GYNB under normoxic conditions and then exposed for 5 h to: (a) 1% lactate; (b) 0% lactate control; (c) hypoxia; or (d) normoxic control. Three independent experiments were performed for each clinical isolate.
Project description:We used Candida albicans lab strain SC5314 to obtain tunicamycin adaptors. We did whole genome sequencing of the adaptors and the parent as well.
